Extra-intestinal salmonellosis in a tertiary care centre in South India
Background and Objectives: Extra-intestinal salmonellosis is associated with higher case fatality and is underestimated in the developing countries like India. Here we present a case series of bacteriologically proven extra-intestinal salmonellosis managed at our institute over the past two years....
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
2024-02-01
|
| Series: | Iranian Journal of Microbiology |
| Subjects: | |
| Online Access: | https://ijm.tums.ac.ir/index.php/ijm/article/view/3920 |
| _version_ | 1827348007207567360 |
|---|---|
| author | Vithiya Ganesan Shyamala Ravikoti Raja Sundaramurthy Monica Raghavan Rajendran Tiruvanamalai |
| author_facet | Vithiya Ganesan Shyamala Ravikoti Raja Sundaramurthy Monica Raghavan Rajendran Tiruvanamalai |
| author_sort | Vithiya Ganesan |
| collection | DOAJ |
| description |
Background and Objectives: Extra-intestinal salmonellosis is associated with higher case fatality and is underestimated in the developing countries like India. Here we present a case series of bacteriologically proven extra-intestinal salmonellosis managed at our institute over the past two years.
Materials and Methods: Retrospective analysis of bacteriologically proven extra-intestinal salmonellosis over two years between January 2020 to December 2021 was carried out. Medical records were reviewed for site of infection, evidence of any underlying or predisposing illnesses and antimicrobial susceptibility report.
Results: Eight patients were diagnosed with extra-intestinal salmonellosis. Male to female ratio was 3:1. Mean age was 44 years. Four were typhoidal and four were nontyphoidal Salmonellae. The extra-intestinal sites involved were purulent aspirates from scrotum, caecum, perianal region, intraperitoneal collection, synovium, and urine. Predisposing factors include chronic myeloid leukemia, HIV and gastric malignancy. All deep seated abscess required surgical intervention. All typhoidal Salmonella (n=4) were sensitive to cotrimoxazole, ampicillin, ceftriaxone. Among nontyphoidal Salmonella, one was resistant to cotrimoxazole; two were resistant to ampicillin, ceftriaxone and three resistant to ciprofloxacin.
Conclusion: The diagnosis of extra-intestinal salmonellosis requires a high degree of clinical suspicion and should be included in the differential diagnosis in patients with deep-seated abscesses.
|
| first_indexed | 2024-03-08T00:02:35Z |
| format | Article |
| id | doaj.art-f9baf8857c2944d0b7881f7f27d1d31e |
| institution | Directory Open Access Journal |
| issn | 2008-3289 2008-4447 |
| language | English |
| last_indexed | 2024-03-08T00:02:35Z |
| publishDate | 2024-02-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Microbiology |
| spelling | doaj.art-f9baf8857c2944d0b7881f7f27d1d31e2024-02-18T04:04:09ZengTehran University of Medical SciencesIranian Journal of Microbiology2008-32892008-44472024-02-0116110.18502/ijm.v16i1.14885Extra-intestinal salmonellosis in a tertiary care centre in South IndiaVithiya Ganesan0Shyamala Ravikoti1Raja Sundaramurthy2Monica Raghavan3Rajendran Tiruvanamalai4Department of Microbiology, Velammal Medical College Hospital and Research Institute (VMCH&RI), Madurai, Tamilnadu, IndiaDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, IndiaDepartment of Microbiology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Hyderabad, Telangana, IndiaSRM Medical College Hospital and Research Centre, Chengalpattu,Tamilnadu, IndiaDepartment of Microbiology, Velammal Medical College Hospital and Research Institute (VMCH&RI), Madurai, Tamilnadu, India Background and Objectives: Extra-intestinal salmonellosis is associated with higher case fatality and is underestimated in the developing countries like India. Here we present a case series of bacteriologically proven extra-intestinal salmonellosis managed at our institute over the past two years. Materials and Methods: Retrospective analysis of bacteriologically proven extra-intestinal salmonellosis over two years between January 2020 to December 2021 was carried out. Medical records were reviewed for site of infection, evidence of any underlying or predisposing illnesses and antimicrobial susceptibility report. Results: Eight patients were diagnosed with extra-intestinal salmonellosis. Male to female ratio was 3:1. Mean age was 44 years. Four were typhoidal and four were nontyphoidal Salmonellae. The extra-intestinal sites involved were purulent aspirates from scrotum, caecum, perianal region, intraperitoneal collection, synovium, and urine. Predisposing factors include chronic myeloid leukemia, HIV and gastric malignancy. All deep seated abscess required surgical intervention. All typhoidal Salmonella (n=4) were sensitive to cotrimoxazole, ampicillin, ceftriaxone. Among nontyphoidal Salmonella, one was resistant to cotrimoxazole; two were resistant to ampicillin, ceftriaxone and three resistant to ciprofloxacin. Conclusion: The diagnosis of extra-intestinal salmonellosis requires a high degree of clinical suspicion and should be included in the differential diagnosis in patients with deep-seated abscesses. https://ijm.tums.ac.ir/index.php/ijm/article/view/3920Salmonellosis;Salmonella enteritidis;Abscess;Pancreatitis |
| spellingShingle | Vithiya Ganesan Shyamala Ravikoti Raja Sundaramurthy Monica Raghavan Rajendran Tiruvanamalai Extra-intestinal salmonellosis in a tertiary care centre in South India Iranian Journal of Microbiology Salmonellosis; Salmonella enteritidis; Abscess; Pancreatitis |
| title | Extra-intestinal salmonellosis in a tertiary care centre in South India |
| title_full | Extra-intestinal salmonellosis in a tertiary care centre in South India |
| title_fullStr | Extra-intestinal salmonellosis in a tertiary care centre in South India |
| title_full_unstemmed | Extra-intestinal salmonellosis in a tertiary care centre in South India |
| title_short | Extra-intestinal salmonellosis in a tertiary care centre in South India |
| title_sort | extra intestinal salmonellosis in a tertiary care centre in south india |
| topic | Salmonellosis; Salmonella enteritidis; Abscess; Pancreatitis |
| url | https://ijm.tums.ac.ir/index.php/ijm/article/view/3920 |
| work_keys_str_mv | AT vithiyaganesan extraintestinalsalmonellosisinatertiarycarecentreinsouthindia AT shyamalaravikoti extraintestinalsalmonellosisinatertiarycarecentreinsouthindia AT rajasundaramurthy extraintestinalsalmonellosisinatertiarycarecentreinsouthindia AT monicaraghavan extraintestinalsalmonellosisinatertiarycarecentreinsouthindia AT rajendrantiruvanamalai extraintestinalsalmonellosisinatertiarycarecentreinsouthindia |