Multisystem inflammatory syndrome in children characterized by enhanced antigen-specific T-cell expression of cytokines and its reversal following recovery

Multisystem inflammatory syndrome in children characterized by enhanced antigen-specific T-cell expression of cytokines and its reversal following recovery

BackgroundMultisystem inflammatory syndrome (MIS) in children is considered to be a post-infectious complication of COVID-19. T-cell responses in children with this condition have not been well-studied.MethodsWe aimed to study the immune responses in children with MIS in comparison to children with...

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Bibliographic Details
Main Authors: Nathella Pavan Kumar, Kadar M. Abbas, Rachel M. Renji, Aishwarya Venkataraman, Arul Nancy, Poovazhagi Varadarjan, Elilarasi Selladurai, Thankgavelu Sangaralingam, Ramya Selvam, Akshith Thimmaiah, Suresh Natarajan, Ganesh Ramasamy, Syed Hissar, Uma Devi Ranganathan, Thomas B. Nutman, Subash Babu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Pediatrics
Subjects:
MIS-C
SARS-CoV-2
COVID-19
CD4+ T cells
CD8+ T cells
cellular immune responses
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1235342/full

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