Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia

Chronic Myelomonocytic Leukemia (CMML) is a blood malignancy that presents with splenomegaly in up to 40% of the patients; however, a pathological splenic rupture is very rare. We describe a 50-year-old male, who presented to emergency room with hypovolemic shock secondary to pathological splenic ru...

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Main Authors: Abdul Muqtadir Abbasi, Salman Adil, Bushra Moiz
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Leukemia Research Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221304892030011X
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author Abdul Muqtadir Abbasi
Salman Adil
Bushra Moiz
author_facet Abdul Muqtadir Abbasi
Salman Adil
Bushra Moiz
author_sort Abdul Muqtadir Abbasi
collection DOAJ
description Chronic Myelomonocytic Leukemia (CMML) is a blood malignancy that presents with splenomegaly in up to 40% of the patients; however, a pathological splenic rupture is very rare. We describe a 50-year-old male, who presented to emergency room with hypovolemic shock secondary to pathological splenic rupture. Patient underwent emergency laparoscopic splenectomy and stabilized. During the stay at hospital, his complete workup revealed the diagnosis of Chronic Myelomonocytic Leukemia. Although splenomegaly is common in CMML, it rarely result in its rupture and so this complication is often overlooked. This case is reviewed in the light of handful cases described in medical literature.
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spelling doaj.art-f9c932ef61a246f98b71f66ab8c189cd2022-12-21T19:00:40ZengElsevierLeukemia Research Reports2213-04892020-01-0114100205Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemiaAbdul Muqtadir Abbasi0Salman Adil1Bushra Moiz2Department of Oncology, Aga Khan University Hospital, Karachi, 75300, Pakistan; Corresponding author.Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, 75300, PakistanDepartment of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, 75300, PakistanChronic Myelomonocytic Leukemia (CMML) is a blood malignancy that presents with splenomegaly in up to 40% of the patients; however, a pathological splenic rupture is very rare. We describe a 50-year-old male, who presented to emergency room with hypovolemic shock secondary to pathological splenic rupture. Patient underwent emergency laparoscopic splenectomy and stabilized. During the stay at hospital, his complete workup revealed the diagnosis of Chronic Myelomonocytic Leukemia. Although splenomegaly is common in CMML, it rarely result in its rupture and so this complication is often overlooked. This case is reviewed in the light of handful cases described in medical literature.http://www.sciencedirect.com/science/article/pii/S221304892030011X
spellingShingle Abdul Muqtadir Abbasi
Salman Adil
Bushra Moiz
Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia
Leukemia Research Reports
title Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia
title_full Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia
title_fullStr Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia
title_full_unstemmed Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia
title_short Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia
title_sort spontaneous splenic rupture an uncommon complication of chronic myelomonocytic leukemia
url http://www.sciencedirect.com/science/article/pii/S221304892030011X
work_keys_str_mv AT abdulmuqtadirabbasi spontaneoussplenicruptureanuncommoncomplicationofchronicmyelomonocyticleukemia
AT salmanadil spontaneoussplenicruptureanuncommoncomplicationofchronicmyelomonocyticleukemia
AT bushramoiz spontaneoussplenicruptureanuncommoncomplicationofchronicmyelomonocyticleukemia