Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia
Chronic Myelomonocytic Leukemia (CMML) is a blood malignancy that presents with splenomegaly in up to 40% of the patients; however, a pathological splenic rupture is very rare. We describe a 50-year-old male, who presented to emergency room with hypovolemic shock secondary to pathological splenic ru...
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Format: | Article |
Language: | English |
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Elsevier
2020-01-01
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Series: | Leukemia Research Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221304892030011X |
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author | Abdul Muqtadir Abbasi Salman Adil Bushra Moiz |
author_facet | Abdul Muqtadir Abbasi Salman Adil Bushra Moiz |
author_sort | Abdul Muqtadir Abbasi |
collection | DOAJ |
description | Chronic Myelomonocytic Leukemia (CMML) is a blood malignancy that presents with splenomegaly in up to 40% of the patients; however, a pathological splenic rupture is very rare. We describe a 50-year-old male, who presented to emergency room with hypovolemic shock secondary to pathological splenic rupture. Patient underwent emergency laparoscopic splenectomy and stabilized. During the stay at hospital, his complete workup revealed the diagnosis of Chronic Myelomonocytic Leukemia. Although splenomegaly is common in CMML, it rarely result in its rupture and so this complication is often overlooked. This case is reviewed in the light of handful cases described in medical literature. |
first_indexed | 2024-12-21T14:25:43Z |
format | Article |
id | doaj.art-f9c932ef61a246f98b71f66ab8c189cd |
institution | Directory Open Access Journal |
issn | 2213-0489 |
language | English |
last_indexed | 2024-12-21T14:25:43Z |
publishDate | 2020-01-01 |
publisher | Elsevier |
record_format | Article |
series | Leukemia Research Reports |
spelling | doaj.art-f9c932ef61a246f98b71f66ab8c189cd2022-12-21T19:00:40ZengElsevierLeukemia Research Reports2213-04892020-01-0114100205Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemiaAbdul Muqtadir Abbasi0Salman Adil1Bushra Moiz2Department of Oncology, Aga Khan University Hospital, Karachi, 75300, Pakistan; Corresponding author.Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, 75300, PakistanDepartment of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, 75300, PakistanChronic Myelomonocytic Leukemia (CMML) is a blood malignancy that presents with splenomegaly in up to 40% of the patients; however, a pathological splenic rupture is very rare. We describe a 50-year-old male, who presented to emergency room with hypovolemic shock secondary to pathological splenic rupture. Patient underwent emergency laparoscopic splenectomy and stabilized. During the stay at hospital, his complete workup revealed the diagnosis of Chronic Myelomonocytic Leukemia. Although splenomegaly is common in CMML, it rarely result in its rupture and so this complication is often overlooked. This case is reviewed in the light of handful cases described in medical literature.http://www.sciencedirect.com/science/article/pii/S221304892030011X |
spellingShingle | Abdul Muqtadir Abbasi Salman Adil Bushra Moiz Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia Leukemia Research Reports |
title | Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia |
title_full | Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia |
title_fullStr | Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia |
title_full_unstemmed | Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia |
title_short | Spontaneous splenic rupture – An uncommon complication of chronic myelomonocytic leukemia |
title_sort | spontaneous splenic rupture an uncommon complication of chronic myelomonocytic leukemia |
url | http://www.sciencedirect.com/science/article/pii/S221304892030011X |
work_keys_str_mv | AT abdulmuqtadirabbasi spontaneoussplenicruptureanuncommoncomplicationofchronicmyelomonocyticleukemia AT salmanadil spontaneoussplenicruptureanuncommoncomplicationofchronicmyelomonocyticleukemia AT bushramoiz spontaneoussplenicruptureanuncommoncomplicationofchronicmyelomonocyticleukemia |