Outpatient screening for gestational diabetes mellitus
Objective: To screen for gestational diabetes mellitus inoutpatients, with 50 g oral glucose load, comparing capillary(reflectance) and venous plasma (enzymatic) glucose. Methods:A cross-sectional clinical trial was conducted on 325 pregnantwomen, between 24 and 28 weeks gestation. The screening cut...
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| Format: | Article |
| Language: | English |
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
2006-12-01
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| Series: | Einstein (São Paulo) |
| Subjects: | |
| Online Access: | http://www.einstein.br/revista/arquivos/PDF/368-Einstein_vol4_n4_2006_p284.pdf |
| _version_ | 1818558424291475456 |
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| author | José Eduardo Gobbi Lima Umberto Gazi Lippi |
| author_facet | José Eduardo Gobbi Lima Umberto Gazi Lippi |
| author_sort | José Eduardo Gobbi Lima |
| collection | DOAJ |
| description | Objective: To screen for gestational diabetes mellitus inoutpatients, with 50 g oral glucose load, comparing capillary(reflectance) and venous plasma (enzymatic) glucose. Methods:A cross-sectional clinical trial was conducted on 325 pregnantwomen, between 24 and 28 weeks gestation. The screening cutoffvalue was ≥ 130 mg/dl and, at this value or greater, the oralglucose tolerance test with 100 grams glucose was performed.This test was interpreted according to the National Diabetes DataGroup and Carpenter and Coustan criteria. A control group of 92pregnant women with the diagnosis of gestational diabetesmellitus was the reference for comparing the time elapsed betweenscreening and diagnosis. For the statistical analysis, the Pearsoncorrelation coefficient and the Student’s t test were utilized.Results: The 50 g glucose screening tests using venous andcapillary blood were correlated. Capillary blood glucose screeningyielded a greater number of diagnoses, with a significant increasein false positive results. Mean capillary blood glucose was 11%greater than mean venous plasma glucose in 82.7% (269/325) ofthe pregnant women. The time elapsed between screening anddiagnosis ranged from 2 to 72 days, and the mean time elapsedwhen capillary blood glucose was utilized was 15.4 days, whilethat for the control group when venous plasma glucose was usedwas 32.5 days (p < 0.05). Conclusion: Utilization of capillaryblood glucose, maintaining the cutoff point of 130 mg/dl,increased the number of diagnoses of gestational diabetes mellitus,although it yielded greater number of false positive results. Thetime elapsed between screening and diagnosis was reduced bythe use of capillary blood glucose. |
| first_indexed | 2024-12-14T00:12:16Z |
| format | Article |
| id | doaj.art-f9cae573ecba4db186e163ba3b94d204 |
| institution | Directory Open Access Journal |
| issn | 1679-4508 |
| language | English |
| last_indexed | 2024-12-14T00:12:16Z |
| publishDate | 2006-12-01 |
| publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
| record_format | Article |
| series | Einstein (São Paulo) |
| spelling | doaj.art-f9cae573ecba4db186e163ba3b94d2042022-12-21T23:25:42ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)1679-45082006-12-0144284289Outpatient screening for gestational diabetes mellitusJosé Eduardo Gobbi LimaUmberto Gazi LippiObjective: To screen for gestational diabetes mellitus inoutpatients, with 50 g oral glucose load, comparing capillary(reflectance) and venous plasma (enzymatic) glucose. Methods:A cross-sectional clinical trial was conducted on 325 pregnantwomen, between 24 and 28 weeks gestation. The screening cutoffvalue was ≥ 130 mg/dl and, at this value or greater, the oralglucose tolerance test with 100 grams glucose was performed.This test was interpreted according to the National Diabetes DataGroup and Carpenter and Coustan criteria. A control group of 92pregnant women with the diagnosis of gestational diabetesmellitus was the reference for comparing the time elapsed betweenscreening and diagnosis. For the statistical analysis, the Pearsoncorrelation coefficient and the Student’s t test were utilized.Results: The 50 g glucose screening tests using venous andcapillary blood were correlated. Capillary blood glucose screeningyielded a greater number of diagnoses, with a significant increasein false positive results. Mean capillary blood glucose was 11%greater than mean venous plasma glucose in 82.7% (269/325) ofthe pregnant women. The time elapsed between screening anddiagnosis ranged from 2 to 72 days, and the mean time elapsedwhen capillary blood glucose was utilized was 15.4 days, whilethat for the control group when venous plasma glucose was usedwas 32.5 days (p < 0.05). Conclusion: Utilization of capillaryblood glucose, maintaining the cutoff point of 130 mg/dl,increased the number of diagnoses of gestational diabetes mellitus,although it yielded greater number of false positive results. Thetime elapsed between screening and diagnosis was reduced bythe use of capillary blood glucose.http://www.einstein.br/revista/arquivos/PDF/368-Einstein_vol4_n4_2006_p284.pdfDiabetes mellitusDiabetesgestationalPublic healthDiagnosis |
| spellingShingle | José Eduardo Gobbi Lima Umberto Gazi Lippi Outpatient screening for gestational diabetes mellitus Einstein (São Paulo) Diabetes mellitus Diabetes gestational Public health Diagnosis |
| title | Outpatient screening for gestational diabetes mellitus |
| title_full | Outpatient screening for gestational diabetes mellitus |
| title_fullStr | Outpatient screening for gestational diabetes mellitus |
| title_full_unstemmed | Outpatient screening for gestational diabetes mellitus |
| title_short | Outpatient screening for gestational diabetes mellitus |
| title_sort | outpatient screening for gestational diabetes mellitus |
| topic | Diabetes mellitus Diabetes gestational Public health Diagnosis |
| url | http://www.einstein.br/revista/arquivos/PDF/368-Einstein_vol4_n4_2006_p284.pdf |
| work_keys_str_mv | AT joseeduardogobbilima outpatientscreeningforgestationaldiabetesmellitus AT umbertogazilippi outpatientscreeningforgestationaldiabetesmellitus |