Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved]
Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-rela...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2023-09-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/12-337/v3 |
| _version_ | 1827823198347984896 |
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| author | Moetemri Zied Samira Mhamdi Ghedira Hela Aida Ayadi Selsabil Daboussi Samia Essebaa Chiraz Aichaouia |
| author_facet | Moetemri Zied Samira Mhamdi Ghedira Hela Aida Ayadi Selsabil Daboussi Samia Essebaa Chiraz Aichaouia |
| author_sort | Moetemri Zied |
| collection | DOAJ |
| description | Idiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-relapsing and steroid-dependent ICEP was made respectively. Mepolizumab was prescribed to both patients. This treatment resulted in successful long-term disease management with much fewer side effects than a traditional corticosteroid therapy. |
| first_indexed | 2024-03-12T02:08:44Z |
| format | Article |
| id | doaj.art-f9ce65787cf5418f879adf5c7f9be5b0 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-03-12T02:08:44Z |
| publishDate | 2023-09-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-f9ce65787cf5418f879adf5c7f9be5b02023-09-07T00:00:00ZengF1000 Research LtdF1000Research2046-14022023-09-0112155328Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved]Moetemri Zied0Samira Mhamdi1https://orcid.org/0000-0003-3284-426XGhedira Hela2Aida Ayadi3Selsabil Daboussi4https://orcid.org/0000-0001-7732-8643Samia Essebaa5Chiraz Aichaouia6University of Tunis El Manar, Tunis, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaPneumology, Military Hospital of Tunis, Tunis, 1008, TunisiaUniversity of Tunis El Manar, Tunis, TunisiaIdiopathic chronic eosinophilic pneumonia (ICEP) is a rare interstitial lung disease of unknown cause. It usually responds well to systemic corticosteroid therapy, but relapses are frequent. We describe two cases of 21- and 27-year-old patients, presenting with dyspnea. The diagnosis of steroid-relapsing and steroid-dependent ICEP was made respectively. Mepolizumab was prescribed to both patients. This treatment resulted in successful long-term disease management with much fewer side effects than a traditional corticosteroid therapy.https://f1000research.com/articles/12-337/v3Mepolizumab Idiopathic chronic eosinophilic pneumonia Corticosteroid Treatmenteng |
| spellingShingle | Moetemri Zied Samira Mhamdi Ghedira Hela Aida Ayadi Selsabil Daboussi Samia Essebaa Chiraz Aichaouia Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved] F1000Research Mepolizumab Idiopathic chronic eosinophilic pneumonia Corticosteroid Treatment eng |
| title | Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved] |
| title_full | Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved] |
| title_fullStr | Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved] |
| title_full_unstemmed | Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved] |
| title_short | Case Report: Mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia [version 3; peer review: 2 approved] |
| title_sort | case report mepolizumab in the treatment of idiopathic chronic eosinophilic pneumonia version 3 peer review 2 approved |
| topic | Mepolizumab Idiopathic chronic eosinophilic pneumonia Corticosteroid Treatment eng |
| url | https://f1000research.com/articles/12-337/v3 |
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