Seasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in South Korea
Abstract The aim of this study was to examine the effect of seasonal changes on the incidence of preeclampsia (PE) in South Korea and East Asian populations, and to evaluate the relationship between upper respiratory infection (URI) during pregnancy and the development of PE. This cohort study inclu...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-06-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-14942-z |
| _version_ | 1818257010174459904 |
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| author | Eui hyeok Kim Sang Ah Lee Seunggi Min Yong Wook Jung |
| author_facet | Eui hyeok Kim Sang Ah Lee Seunggi Min Yong Wook Jung |
| author_sort | Eui hyeok Kim |
| collection | DOAJ |
| description | Abstract The aim of this study was to examine the effect of seasonal changes on the incidence of preeclampsia (PE) in South Korea and East Asian populations, and to evaluate the relationship between upper respiratory infection (URI) during pregnancy and the development of PE. This cohort study included women who had singleton births between 2012 and 2018 in South Korea. A total of 548,080 first singleton births were analyzed, and 9311 patients (1.70%) were diagnosed with PE. Multivariate analysis showed that older age (≥ 30 years old), low income, residing in the southern part of South Korea, history of cigarette smoking, heavy drinking, higher body mass index, hypertension, or diabetes mellitus were risk factors for PE. Univariate analysis showed that URI was associated with the incidence of PE (P = 0.0294). However, this association was not statistically significant in the multivariate analysis (aOR 1.01; 95% CI 0.95–1.07). After adjusting for confounding variables, the occurrence of PE was the highest in December (aOR 1.21; 95% CI 1.10–1.34) and lowest in July and August. This study demonstrated that there are seasonal variations in the occurrence of PE in South Korea. Moreover, URI may be associated with the development of PE. |
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| format | Article |
| id | doaj.art-f9d0c700eb25401da1b22f89a8e8927a |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-12T17:36:51Z |
| publishDate | 2022-06-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj.art-f9d0c700eb25401da1b22f89a8e8927a2022-12-22T00:17:12ZengNature PortfolioScientific Reports2045-23222022-06-011211810.1038/s41598-022-14942-zSeasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in South KoreaEui hyeok Kim0Sang Ah Lee1Seunggi Min2Yong Wook Jung3Department of Obstetrics and Gynecology, National Health Insurance Service Ilsan HospitalKorea Research and Analysis Team, National Health Insurance Service Ilsan HospitalDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA UniversityDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA UniversityAbstract The aim of this study was to examine the effect of seasonal changes on the incidence of preeclampsia (PE) in South Korea and East Asian populations, and to evaluate the relationship between upper respiratory infection (URI) during pregnancy and the development of PE. This cohort study included women who had singleton births between 2012 and 2018 in South Korea. A total of 548,080 first singleton births were analyzed, and 9311 patients (1.70%) were diagnosed with PE. Multivariate analysis showed that older age (≥ 30 years old), low income, residing in the southern part of South Korea, history of cigarette smoking, heavy drinking, higher body mass index, hypertension, or diabetes mellitus were risk factors for PE. Univariate analysis showed that URI was associated with the incidence of PE (P = 0.0294). However, this association was not statistically significant in the multivariate analysis (aOR 1.01; 95% CI 0.95–1.07). After adjusting for confounding variables, the occurrence of PE was the highest in December (aOR 1.21; 95% CI 1.10–1.34) and lowest in July and August. This study demonstrated that there are seasonal variations in the occurrence of PE in South Korea. Moreover, URI may be associated with the development of PE.https://doi.org/10.1038/s41598-022-14942-z |
| spellingShingle | Eui hyeok Kim Sang Ah Lee Seunggi Min Yong Wook Jung Seasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in South Korea Scientific Reports |
| title | Seasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in South Korea |
| title_full | Seasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in South Korea |
| title_fullStr | Seasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in South Korea |
| title_full_unstemmed | Seasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in South Korea |
| title_short | Seasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in South Korea |
| title_sort | seasonal variations in the occurrence of preeclampsia and potential implication of upper respiratory infections in south korea |
| url | https://doi.org/10.1038/s41598-022-14942-z |
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