Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022
Upon declaration of poliovirus (PV) type 2 eradication in 2015, the World Health Organization (WHO) published PV containment requirements in the Global Action Plan III (GAPIII) for mitigating the risk of a facility-associated release post eradication. In 2018, the 71st World Health Assembly resoluti...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/13/2/116 |
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| author | Christy Ottendorfer Bryan Shelby Cecelia A. Sanders Anna Llewellyn Christy Myrick Christye Brown Suganthi Suppiah Kortney Gustin Lia Haynes Smith |
| author_facet | Christy Ottendorfer Bryan Shelby Cecelia A. Sanders Anna Llewellyn Christy Myrick Christye Brown Suganthi Suppiah Kortney Gustin Lia Haynes Smith |
| author_sort | Christy Ottendorfer |
| collection | DOAJ |
| description | Upon declaration of poliovirus (PV) type 2 eradication in 2015, the World Health Organization (WHO) published PV containment requirements in the Global Action Plan III (GAPIII) for mitigating the risk of a facility-associated release post eradication. In 2018, the 71st World Health Assembly resolution urged member states retaining PV to appoint a National Authority for Containment (NAC), reduce the number of PV facilities, and submit applications for containment certification. The United States (US) NAC was established in 2018 for containment oversight, and two paths to WHO GAPIII containment certification were developed. Facilities retaining PV were identified through national poliovirus containment surveys. The US NAC conducted 27 site visits at 18 facilities (20 laboratories: A/BSL-2 (65%), A/BSL-3 (20%), and storage-only (15%)) to verify the implementation of US NAC’s preliminary containment measures. The NAC identified areas for improvement in seven categories: primary containment, decontamination, hand hygiene, security, emergency response, training, and immunization practices. Sixteen facility applications were endorsed to pursue poliovirus-essential facility (PEF) certification, whereas four facilities opted to withdraw during the containment certification process. The US made noteworthy progress in PV containment to enhance biosafety and biosecurity practices at US PV facilities to safeguard the polio eradication effort. |
| first_indexed | 2024-03-07T22:18:56Z |
| format | Article |
| id | doaj.art-f9d1f886fb9e49e1b22ca8d84d4afb19 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-07T22:18:56Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-f9d1f886fb9e49e1b22ca8d84d4afb192024-02-23T15:30:15ZengMDPI AGPathogens2076-08172024-01-0113211610.3390/pathogens13020116Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022Christy Ottendorfer0Bryan Shelby1Cecelia A. Sanders2Anna Llewellyn3Christy Myrick4Christye Brown5Suganthi Suppiah6Kortney Gustin7Lia Haynes Smith8Centers for Disease Control and Prevention, Office of Readiness and Response, U.S. National Authority for Containment of Poliovirus, Atlanta, GA 30329, USACenters for Disease Control and Prevention, Office of Readiness and Response, U.S. National Authority for Containment of Poliovirus, Atlanta, GA 30329, USACenters for Disease Control and Prevention, Office of Readiness and Response, U.S. National Authority for Containment of Poliovirus, Atlanta, GA 30329, USACenters for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Atlanta, GA 30329, USACenters for Disease Control and Prevention, Office of Laboratory Science and Safety, Atlanta, GA 30329, USAMorehouse School of Medicine, Atlanta, GA 30310, USACenters for Disease Control and Prevention, Office of Readiness and Response, U.S. National Authority for Containment of Poliovirus, Atlanta, GA 30329, USACenters for Disease Control and Prevention, Office of Readiness and Response, U.S. National Authority for Containment of Poliovirus, Atlanta, GA 30329, USACenters for Disease Control and Prevention, Office of Readiness and Response, U.S. National Authority for Containment of Poliovirus, Atlanta, GA 30329, USAUpon declaration of poliovirus (PV) type 2 eradication in 2015, the World Health Organization (WHO) published PV containment requirements in the Global Action Plan III (GAPIII) for mitigating the risk of a facility-associated release post eradication. In 2018, the 71st World Health Assembly resolution urged member states retaining PV to appoint a National Authority for Containment (NAC), reduce the number of PV facilities, and submit applications for containment certification. The United States (US) NAC was established in 2018 for containment oversight, and two paths to WHO GAPIII containment certification were developed. Facilities retaining PV were identified through national poliovirus containment surveys. The US NAC conducted 27 site visits at 18 facilities (20 laboratories: A/BSL-2 (65%), A/BSL-3 (20%), and storage-only (15%)) to verify the implementation of US NAC’s preliminary containment measures. The NAC identified areas for improvement in seven categories: primary containment, decontamination, hand hygiene, security, emergency response, training, and immunization practices. Sixteen facility applications were endorsed to pursue poliovirus-essential facility (PEF) certification, whereas four facilities opted to withdraw during the containment certification process. The US made noteworthy progress in PV containment to enhance biosafety and biosecurity practices at US PV facilities to safeguard the polio eradication effort.https://www.mdpi.com/2076-0817/13/2/116polioGAPIIIpoliovirus containmentNACpoliovirus-essential facilityPEF |
| spellingShingle | Christy Ottendorfer Bryan Shelby Cecelia A. Sanders Anna Llewellyn Christy Myrick Christye Brown Suganthi Suppiah Kortney Gustin Lia Haynes Smith Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022 Pathogens polio GAPIII poliovirus containment NAC poliovirus-essential facility PEF |
| title | Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022 |
| title_full | Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022 |
| title_fullStr | Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022 |
| title_full_unstemmed | Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022 |
| title_short | Establishment of a Poliovirus Containment Program and Containment Certification Process for Poliovirus-Essential Facilities, United States 2017–2022 |
| title_sort | establishment of a poliovirus containment program and containment certification process for poliovirus essential facilities united states 2017 2022 |
| topic | polio GAPIII poliovirus containment NAC poliovirus-essential facility PEF |
| url | https://www.mdpi.com/2076-0817/13/2/116 |
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