Non thrombotic antiphospholipid syndrome: neurologic and hematologic inflammatory manifestations

Antiphospholipid syndrome (APS) is an entity defined for the presence of antiphospholipid antibodies and events such as recurrent fetal loss and arterial or ve-nous thrombosis. APS diagnosis is made through clas-sification criteria, including laboratory criteria and clinical manifestat...

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Main Authors: Álvarez, José Carlos, Ardila, Mario, Urrego-Callejas, Tomás
Format: Article
Language:Spanish
Published: Universidad de Antioquia 2021-10-01
Series:Iatreia
Subjects:
Online Access:https://revistas.udea.edu.co/index.php/iatreia/article/view/342707/20805022
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author Álvarez, José Carlos
Ardila, Mario
Urrego-Callejas, Tomás
author_facet Álvarez, José Carlos
Ardila, Mario
Urrego-Callejas, Tomás
author_sort Álvarez, José Carlos
collection DOAJ
description Antiphospholipid syndrome (APS) is an entity defined for the presence of antiphospholipid antibodies and events such as recurrent fetal loss and arterial or ve-nous thrombosis. APS diagnosis is made through clas-sification criteria, including laboratory criteria and clinical manifestations (most of them being throm-botic manifestations). Nonetheless, there is a wide variety of non-thrombotic manifestations of APS, which are not included in classification criteria. These “non-criteria” manifestations are important for decision making, based on their frequency or clinical relevan-ce. Among them, some domains stand out: the hematologic domain, being thrombocytopenia the main manifestation; and the neurological domain with different manifestations such as migraine, epilepsy, dementia and severe manifestations, such as chorea and myelitis. Therefore, in the present article, information concerning two of the most common “noncriteria” domains (neurological and hematological) of APS is reviewed.
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spelling doaj.art-f9d774de76764375b5abba73ce19c2c92022-12-21T21:26:00ZspaUniversidad de AntioquiaIatreia0121-07932011-79652021-10-0134434735510.17533/udea.iatreia.108Non thrombotic antiphospholipid syndrome: neurologic and hematologic inflammatory manifestationsÁlvarez, José Carlos0Ardila, Mario1 Urrego-Callejas, Tomás2 Universidad de Antioquia, Medellín, Colombia.Universidad de Antioquia, Medellín, Colombia.Universidad de Antioquia, Medellín, Colombia.Antiphospholipid syndrome (APS) is an entity defined for the presence of antiphospholipid antibodies and events such as recurrent fetal loss and arterial or ve-nous thrombosis. APS diagnosis is made through clas-sification criteria, including laboratory criteria and clinical manifestations (most of them being throm-botic manifestations). Nonetheless, there is a wide variety of non-thrombotic manifestations of APS, which are not included in classification criteria. These “non-criteria” manifestations are important for decision making, based on their frequency or clinical relevan-ce. Among them, some domains stand out: the hematologic domain, being thrombocytopenia the main manifestation; and the neurological domain with different manifestations such as migraine, epilepsy, dementia and severe manifestations, such as chorea and myelitis. Therefore, in the present article, information concerning two of the most common “noncriteria” domains (neurological and hematological) of APS is reviewed.https://revistas.udea.edu.co/index.php/iatreia/article/view/342707/20805022antiphospholipid syndromechoreadementiaepilepsyheadachemyelitithrombocytopenia
spellingShingle Álvarez, José Carlos
Ardila, Mario
Urrego-Callejas, Tomás
Non thrombotic antiphospholipid syndrome: neurologic and hematologic inflammatory manifestations
Iatreia
antiphospholipid syndrome
chorea
dementia
epilepsy
headache
myeliti
thrombocytopenia
title Non thrombotic antiphospholipid syndrome: neurologic and hematologic inflammatory manifestations
title_full Non thrombotic antiphospholipid syndrome: neurologic and hematologic inflammatory manifestations
title_fullStr Non thrombotic antiphospholipid syndrome: neurologic and hematologic inflammatory manifestations
title_full_unstemmed Non thrombotic antiphospholipid syndrome: neurologic and hematologic inflammatory manifestations
title_short Non thrombotic antiphospholipid syndrome: neurologic and hematologic inflammatory manifestations
title_sort non thrombotic antiphospholipid syndrome neurologic and hematologic inflammatory manifestations
topic antiphospholipid syndrome
chorea
dementia
epilepsy
headache
myeliti
thrombocytopenia
url https://revistas.udea.edu.co/index.php/iatreia/article/view/342707/20805022
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AT urregocallejastomas nonthromboticantiphospholipidsyndromeneurologicandhematologicinflammatorymanifestations