A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures

Abstract Background We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenu...

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Main Authors: Ben Warner, Phillip Harrison, Muhammad Farman, John Devlin, David Reffitt, Yasser El-Sherif, Shirin E. Khorsandi, Andreas Prachalias, Miriam Cortes Cerisuelo, Krish Menon, Wayel Jassem, Parthi Srinivasan, Hector Vilca-Melendez, Michael Heneghan, Nigel Heaton, Deepak Joshi
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Gastroenterology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12876-020-01479-6
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author Ben Warner
Phillip Harrison
Muhammad Farman
John Devlin
David Reffitt
Yasser El-Sherif
Shirin E. Khorsandi
Andreas Prachalias
Miriam Cortes Cerisuelo
Krish Menon
Wayel Jassem
Parthi Srinivasan
Hector Vilca-Melendez
Michael Heneghan
Nigel Heaton
Deepak Joshi
author_facet Ben Warner
Phillip Harrison
Muhammad Farman
John Devlin
David Reffitt
Yasser El-Sherif
Shirin E. Khorsandi
Andreas Prachalias
Miriam Cortes Cerisuelo
Krish Menon
Wayel Jassem
Parthi Srinivasan
Hector Vilca-Melendez
Michael Heneghan
Nigel Heaton
Deepak Joshi
author_sort Ben Warner
collection DOAJ
description Abstract Background We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum. Methods Sixty-two patients underwent ERCP and Kaffes stent insertion for post-transplant anastomotic strictures following confirmation of a stricture on MRCP. These patients were retrospectively analysed for immediate and long-term stricture resolution, improvement in symptoms and liver function tests (LFTs), stricture recurrence and complication rates. Results Of the 56 patients who had their stent removed at the time of analysis, 54 (96%) had immediate stricture resolution and 42 continued to have long-term resolution (mean follow-up period was 548 days). Of the 16 patients with symptoms of biliary obstruction, 13 had resolution of their symptoms. Overall, there was a significant improvement in LFTs after stent removal compared to before stent insertion. Complication rates were 15% with only one patient requiring biliary reconstruction. Conclusions The Kaffes stent is effective and safe at resolving post liver transplant biliary anastomotic strictures.
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spelling doaj.art-f9d7e0f0970a4e82b51c0697c926b1802022-12-21T20:16:15ZengBMCBMC Gastroenterology1471-230X2020-10-012011610.1186/s12876-020-01479-6A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic stricturesBen Warner0Phillip Harrison1Muhammad Farman2John Devlin3David Reffitt4Yasser El-Sherif5Shirin E. Khorsandi6Andreas Prachalias7Miriam Cortes Cerisuelo8Krish Menon9Wayel Jassem10Parthi Srinivasan11Hector Vilca-Melendez12Michael Heneghan13Nigel Heaton14Deepak Joshi15Institute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustInstitute of Liver Studies, King’s College Hospital NHS Foundation TrustAbstract Background We report our experience of treating anastomotic strictures using a novel type of fully covered metal stent (FCSEMS). This stent, known as the Kaffes Stent, is short-length with an antimigration waist and is easily removable due to long retrieval wires deployed within the duodenum. Methods Sixty-two patients underwent ERCP and Kaffes stent insertion for post-transplant anastomotic strictures following confirmation of a stricture on MRCP. These patients were retrospectively analysed for immediate and long-term stricture resolution, improvement in symptoms and liver function tests (LFTs), stricture recurrence and complication rates. Results Of the 56 patients who had their stent removed at the time of analysis, 54 (96%) had immediate stricture resolution and 42 continued to have long-term resolution (mean follow-up period was 548 days). Of the 16 patients with symptoms of biliary obstruction, 13 had resolution of their symptoms. Overall, there was a significant improvement in LFTs after stent removal compared to before stent insertion. Complication rates were 15% with only one patient requiring biliary reconstruction. Conclusions The Kaffes stent is effective and safe at resolving post liver transplant biliary anastomotic strictures.http://link.springer.com/article/10.1186/s12876-020-01479-6ERCPAnastomotic stricturesFCSEMSBiliary
spellingShingle Ben Warner
Phillip Harrison
Muhammad Farman
John Devlin
David Reffitt
Yasser El-Sherif
Shirin E. Khorsandi
Andreas Prachalias
Miriam Cortes Cerisuelo
Krish Menon
Wayel Jassem
Parthi Srinivasan
Hector Vilca-Melendez
Michael Heneghan
Nigel Heaton
Deepak Joshi
A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
BMC Gastroenterology
ERCP
Anastomotic strictures
FCSEMS
Biliary
title A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_full A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_fullStr A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_full_unstemmed A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_short A unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
title_sort unique type of fully covered metal stent for the management of post liver transplant biliary anastomotic strictures
topic ERCP
Anastomotic strictures
FCSEMS
Biliary
url http://link.springer.com/article/10.1186/s12876-020-01479-6
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