The Choroidal Vascularity Index Versus Optical Coherence Tomography Angiography in the Evaluation of the Choroid with a Focus on Age-Related Macular Degeneration
The choroid is the most vascularized structure of the eye and it is fundamental for the trophism of the outer retina. Its proper functioning and homeostasis represent key points in maintaining normal retinal physiology. Choroidal alterations may be implicated in the development and progression of nu...
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| Format: | Article |
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MDPI AG
2023-08-01
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| Series: | Tomography |
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| Online Access: | https://www.mdpi.com/2379-139X/9/4/116 |
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| author | Mariachiara Di Pippo Claudia Santia Daria Rullo Chiara Ciancimino Flaminia Grassi Solmaz Abdolrahimzadeh |
| author_facet | Mariachiara Di Pippo Claudia Santia Daria Rullo Chiara Ciancimino Flaminia Grassi Solmaz Abdolrahimzadeh |
| author_sort | Mariachiara Di Pippo |
| collection | DOAJ |
| description | The choroid is the most vascularized structure of the eye and it is fundamental for the trophism of the outer retina. Its proper functioning and homeostasis represent key points in maintaining normal retinal physiology. Choroidal alterations may be implicated in the development and progression of numerous pathologies; therefore, in-depth studies using imaging techniques can be of crucial relevance to understanding the pathophysiology of retinal-choroidal diseases. The advent of spectral-domain optical coherence tomography (SDOCT) has enabled the non-invasive study of the choroid in vivo and the most recent development, optical coherence tomography angiography (OCTA), allows for the high-resolution visualization of the choriocapillaris and the choroid in regard to vascularization. The choroidal vascularity index (CVI) is a new parameter calculated on SDOCT scans and is defined as the ratio of the luminal area to the total choroidal area. In this review, a study of the choroid using OCTA and CVI will be evaluated in depth and the pros and cons of these two methods will be analyzed, with a particular focus on age-related macular degeneration. |
| first_indexed | 2024-03-10T23:32:11Z |
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| institution | Directory Open Access Journal |
| issn | 2379-1381 2379-139X |
| language | English |
| last_indexed | 2024-03-10T23:32:11Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tomography |
| spelling | doaj.art-f9d9183fbebc430db5fd8146499bdaae2023-11-19T03:13:54ZengMDPI AGTomography2379-13812379-139X2023-08-01941456147010.3390/tomography9040116The Choroidal Vascularity Index Versus Optical Coherence Tomography Angiography in the Evaluation of the Choroid with a Focus on Age-Related Macular DegenerationMariachiara Di Pippo0Claudia Santia1Daria Rullo2Chiara Ciancimino3Flaminia Grassi4Solmaz Abdolrahimzadeh5Ophthalmology Unit, Neurosciences, Mental Health, and Sense Organs (NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyOphthalmology Unit, Neurosciences, Mental Health, and Sense Organs (NESMOS) Department, Faculty of Medicine and Psychology, University of Rome Sapienza, St. Andrea Hospital, 00189 Rome, ItalyThe choroid is the most vascularized structure of the eye and it is fundamental for the trophism of the outer retina. Its proper functioning and homeostasis represent key points in maintaining normal retinal physiology. Choroidal alterations may be implicated in the development and progression of numerous pathologies; therefore, in-depth studies using imaging techniques can be of crucial relevance to understanding the pathophysiology of retinal-choroidal diseases. The advent of spectral-domain optical coherence tomography (SDOCT) has enabled the non-invasive study of the choroid in vivo and the most recent development, optical coherence tomography angiography (OCTA), allows for the high-resolution visualization of the choriocapillaris and the choroid in regard to vascularization. The choroidal vascularity index (CVI) is a new parameter calculated on SDOCT scans and is defined as the ratio of the luminal area to the total choroidal area. In this review, a study of the choroid using OCTA and CVI will be evaluated in depth and the pros and cons of these two methods will be analyzed, with a particular focus on age-related macular degeneration.https://www.mdpi.com/2379-139X/9/4/116choroidal vascularity indexoptical coherence tomography angiographyspectral-domain optical coherence tomographychoroidage-related macular degenerationmultimodal retinal imaging |
| spellingShingle | Mariachiara Di Pippo Claudia Santia Daria Rullo Chiara Ciancimino Flaminia Grassi Solmaz Abdolrahimzadeh The Choroidal Vascularity Index Versus Optical Coherence Tomography Angiography in the Evaluation of the Choroid with a Focus on Age-Related Macular Degeneration Tomography choroidal vascularity index optical coherence tomography angiography spectral-domain optical coherence tomography choroid age-related macular degeneration multimodal retinal imaging |
| title | The Choroidal Vascularity Index Versus Optical Coherence Tomography Angiography in the Evaluation of the Choroid with a Focus on Age-Related Macular Degeneration |
| title_full | The Choroidal Vascularity Index Versus Optical Coherence Tomography Angiography in the Evaluation of the Choroid with a Focus on Age-Related Macular Degeneration |
| title_fullStr | The Choroidal Vascularity Index Versus Optical Coherence Tomography Angiography in the Evaluation of the Choroid with a Focus on Age-Related Macular Degeneration |
| title_full_unstemmed | The Choroidal Vascularity Index Versus Optical Coherence Tomography Angiography in the Evaluation of the Choroid with a Focus on Age-Related Macular Degeneration |
| title_short | The Choroidal Vascularity Index Versus Optical Coherence Tomography Angiography in the Evaluation of the Choroid with a Focus on Age-Related Macular Degeneration |
| title_sort | choroidal vascularity index versus optical coherence tomography angiography in the evaluation of the choroid with a focus on age related macular degeneration |
| topic | choroidal vascularity index optical coherence tomography angiography spectral-domain optical coherence tomography choroid age-related macular degeneration multimodal retinal imaging |
| url | https://www.mdpi.com/2379-139X/9/4/116 |
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