Thrombin–Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis
Fibrinogen is a well-known risk factor for arterial and venous thrombosis. Its function is not restricted to clot formation, however, as it partakes in a complex interplay between thrombin, soluble plasma fibrinogen, and deposited fibrin matrices. Fibrinogen, like thrombin, participates predominantl...
Main Authors: | Anne-Marije Hulshof, H. Coenraad Hemker, Henri M. H. Spronk, Yvonne M. C. Henskens, Hugo ten Cate |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/5/2590 |
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