Dexamethasone Treatment Preserves the Structure of Adult Cardiac Explants and Supports Their Long-Term Contractility In Vitro

Dexamethasone Treatment Preserves the Structure of Adult Cardiac Explants and Supports Their Long-Term Contractility In Vitro

Normal contractile function of the myocardium is essential for optimal cardiovascular health. Evaluating drug effects on cardiomyocyte function at the cellular level is difficult for long-term studies. Present culture systems rely on isolated, cardiomyocyte preparations or cardiomyocytes derived fro...

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Bibliographic Details
Main Authors: Leonard M. Eisenberg, Keerat Kaur, John M. Castillo, John G. Edwards, Carol A. Eisenberg
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Translational Medicine
Subjects:
heart
cardiac
myocyte
cell culture
contractility
dexamethasone
Online Access:https://www.mdpi.com/2673-8937/3/3/25

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