Helicobacter pylori activates HMGB1 expression and recruits RAGE into lipid rafts to promote inflammation in gastric epithelial cells

Helicobacter pylori activates HMGB1 expression and recruits RAGE into lipid rafts to promote inflammation in gastric epithelial cells

Helicobacter pylori infection is associated with several gastrointestinal disorders in the human population worldwide. High-mobility group box 1 (HMGB1), a ubiquitous nuclear protein, mediates a variety of inflammation functions. The interaction between HMGB1 and receptor for advanced glycation end-...

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Bibliographic Details
Main Authors: Hwai-Jeng Lin, Fang-Yu Hsu, Wei-Wei Chen, Che-Hsin Lee, Ying-Ju Lin, Yi-Ywan M. Chen, Chih-Jung Chen, Mei-Zi Huang, Min-Chuan Kao, Yu-An Chen, Hsin-Chih Lai, Chih-Ho Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Cholesterol
Helicobacter pylori
Interleukin-8
Rage
HMGB1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00341/full

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