Blocked conversion of Lactobacillus johnsonii derived acetate to butyrate mediates copper-induced epithelial barrier damage in a pig model

Blocked conversion of Lactobacillus johnsonii derived acetate to butyrate mediates copper-induced epithelial barrier damage in a pig model

Abstract Background High-copper diets have been widely used to promote growth performance of pigs, but excess copper supplementation can also produce negative effects on ecosystem stability and organism health. High-copper supplementation can damage the intestinal barrier and disturb the gut microbi...

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Bibliographic Details
Main Authors: Yang Wen, Luqing Yang, Zhenyu Wang, Xiaoyi Liu, Meng Gao, Yunhui Zhang, Junjun Wang, Pingli He
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Microbiome
Subjects:
Lactobacillus johnsonii
Colonic barrier
Short-chain fatty acid
Microbiota
Copper
Online Access:https://doi.org/10.1186/s40168-023-01655-2

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