Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia)
<p>A 15.5 year old male white-faced saki (<em>Pithecia pithecia</em>) was euthanized due to severe emaciation and an ultrasonographically suspected hepatic neoplasm. Postmortem examination revealed disseminated granulomatous inflammation affecting liver, pancreas, kidneys, heart, s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | deu |
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Schlütersche Fachmedien GmbH
2022-01-01
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| Series: | Berliner und Münchener Tierärztliche Wochenschrift |
| Subjects: | |
| Online Access: | https://dx.doi.org/10.2376/1439-0299-2021-24 |
| _version_ | 1811249712412491776 |
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| author | M Peters P Wohlsein C Osmann I Moser S Barth |
| author_facet | M Peters P Wohlsein C Osmann I Moser S Barth |
| author_sort | M Peters |
| collection | DOAJ |
| description | <p>A 15.5 year old male white-faced saki (<em>Pithecia pithecia</em>) was euthanized due to severe emaciation and an ultrasonographically suspected hepatic neoplasm. Postmortem examination revealed disseminated granulomatous inflammation affecting liver, pancreas, kidneys, heart, skin, and various lymph nodes. Mycobacteria were isolated from pulmonary lymph node and liver, identified as <em>Mycobacterium (M.) xenopi</em> a non-tuberculous mycobacterial species of human relevance especially in cases of underlying immunodeficiency. Subsequent characterization using ITS-sequencing and MLST-pattern analysis revealed that the isolate was identical with a Canadian strain of human origin indicating a high degree of conservation across countries and host species. This case represents to our knowledge the first report of a clinical <em>M. xenopi</em> infection in a host species not yet reported.</p> |
| first_indexed | 2024-04-12T15:51:20Z |
| format | Article |
| id | doaj.art-f9e2025ec28848b0958184346bbc6808 |
| institution | Directory Open Access Journal |
| issn | 1439-0299 |
| language | deu |
| last_indexed | 2024-04-12T15:51:20Z |
| publishDate | 2022-01-01 |
| publisher | Schlütersche Fachmedien GmbH |
| record_format | Article |
| series | Berliner und Münchener Tierärztliche Wochenschrift |
| spelling | doaj.art-f9e2025ec28848b0958184346bbc68082022-12-22T03:26:29ZdeuSchlütersche Fachmedien GmbHBerliner und Münchener Tierärztliche Wochenschrift1439-02992022-01-0113510.2376/1439-0299-2021-24Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia)M PetersP WohlseinC OsmannI MoserS Barth<p>A 15.5 year old male white-faced saki (<em>Pithecia pithecia</em>) was euthanized due to severe emaciation and an ultrasonographically suspected hepatic neoplasm. Postmortem examination revealed disseminated granulomatous inflammation affecting liver, pancreas, kidneys, heart, skin, and various lymph nodes. Mycobacteria were isolated from pulmonary lymph node and liver, identified as <em>Mycobacterium (M.) xenopi</em> a non-tuberculous mycobacterial species of human relevance especially in cases of underlying immunodeficiency. Subsequent characterization using ITS-sequencing and MLST-pattern analysis revealed that the isolate was identical with a Canadian strain of human origin indicating a high degree of conservation across countries and host species. This case represents to our knowledge the first report of a clinical <em>M. xenopi</em> infection in a host species not yet reported.</p>https://dx.doi.org/10.2376/1439-0299-2021-24Mycobacterium xenopinon-human primateITS-sequencingMLST-pattern |
| spellingShingle | M Peters P Wohlsein C Osmann I Moser S Barth Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia) Berliner und Münchener Tierärztliche Wochenschrift Mycobacterium xenopi non-human primate ITS-sequencing MLST-pattern |
| title | Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia) |
| title_full | Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia) |
| title_fullStr | Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia) |
| title_full_unstemmed | Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia) |
| title_short | Disseminated atypical Mycobacteriosis caused by Mycobacterium xenopi in a White-Faced Saki (Pithecia pithecia) |
| title_sort | disseminated atypical mycobacteriosis caused by mycobacterium xenopi in a white faced saki pithecia pithecia |
| topic | Mycobacterium xenopi non-human primate ITS-sequencing MLST-pattern |
| url | https://dx.doi.org/10.2376/1439-0299-2021-24 |
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