Aging‐related hyperphosphatemia impairs myogenic differentiation and enhances fibrosis in skeletal muscle

Aging‐related hyperphosphatemia impairs myogenic differentiation and enhances fibrosis in skeletal muscle

Abstract Background Hyperphosphatemia has been related to the development of sarcopenia in aging mice. We describe the intracellular mechanisms involved in the impairment of the myogenic differentiation promoted by hyperphosphatemia and analyse these mechanisms in the muscle from older mice. Methods...

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Bibliographic Details
Main Authors: Patricia Sosa, Elena Alcalde‐Estévez, Ana Asenjo‐Bueno, Patricia Plaza, Natalia Carrillo‐López, Gemma Olmos, Susana López‐Ongil, María Piedad Ruiz‐Torres
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Hyperphosphatemia
Myogenic differentiation
Skeletal muscle
Muscular fibrosis
Online Access:https://doi.org/10.1002/jcsm.12750

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