Risk factors for uncontrolled asthma in adults
Background: Many studies in children had identified risk factors associated with partly or uncontrolled asthma. In adults, factors related to asthma control were not well defined. Objective: To find the factors related to partly or uncontrolled asthma in adults. Methods: Asthmatic adults who had s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
2019-04-01
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| Series: | Revista Alergia México |
| Subjects: | |
| Online Access: | http://revistaalergia.mx/ojs/index.php/ram/article/view/557 |
| _version_ | 1827835997726965760 |
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| author | Juan Carlos Fernández de Córdova-Aguirre Andrea Aída Velasco-Medina César Urquiza Karol Andrea Guzmán-Guillén Guillermo Velázquez-Sámano |
| author_facet | Juan Carlos Fernández de Córdova-Aguirre Andrea Aída Velasco-Medina César Urquiza Karol Andrea Guzmán-Guillén Guillermo Velázquez-Sámano |
| author_sort | Juan Carlos Fernández de Córdova-Aguirre |
| collection | DOAJ |
| description | Background: Many studies in children had identified risk factors associated with partly or uncontrolled asthma. In adults, factors related to asthma control were not well defined.
Objective: To find the factors related to partly or uncontrolled asthma in adults.
Methods: Asthmatic adults who had severity at least in the mild persistent level, were recruited. The asthma control levels were classified as controlled, partly controlled and uncontrolled according to the Global Initiative for Asthma guideline. Risk factors were compared between the patients with controlled and partly controlled/ uncontrolled asthma groups.
Results: two hundred (75.5 % females) were included. The mean age was 38.4 ± 11.93 years old. There were 100 patients (50 %) in the controlled and 100 patients (50 %) in partly controlled and uncontrolled asthma group. For asthma severity, 35 patients (88.2 %) were in mild persistent, 14 patients (10 %) in moderate persistent and 97 patients (1.8 %) in severe persistent groups. The absence of stress yielded an OR = 0.41 (95 % CI = 0.23-0.75), p = 0.03. While active smoking, OR = 4.23 (95 % CI = 1.35-13.2), p = 0.007. Patients who have no contact with stuffed animals or rugs have OR = 0.4 (IC 95 % = 0.2-0.79). It was important the result of the patients that if they correctly use their inhalers OR = 0.36 (IC 95 % = 0.13-0.97), p = 0.031.
Conclusions: Current and active smoking and atopic dermatitis are risk factors. As a protective factor to the normal levels of eosinophils in blood, correct use of inhalers, FEV1 > 80 %, the absence of stress and the absence of contact with carpets and stuffed animals. |
| first_indexed | 2024-03-12T06:18:17Z |
| format | Article |
| id | doaj.art-f9e2ffe129cb438ba86e490c92f2196d |
| institution | Directory Open Access Journal |
| issn | 0002-5151 2448-9190 |
| language | English |
| last_indexed | 2024-03-12T06:18:17Z |
| publishDate | 2019-04-01 |
| publisher | Colegio Mexicano de Inmunología Clínica y Alergia, A.C. |
| record_format | Article |
| series | Revista Alergia México |
| spelling | doaj.art-f9e2ffe129cb438ba86e490c92f2196d2023-09-03T02:24:40ZengColegio Mexicano de Inmunología Clínica y Alergia, A.C.Revista Alergia México0002-51512448-91902019-04-01661657510.29262/ram.v66i1.557401Risk factors for uncontrolled asthma in adultsJuan Carlos Fernández de Córdova-Aguirre0Andrea Aída Velasco-Medina1César Urquiza2Karol Andrea Guzmán-Guillén3Guillermo Velázquez-Sámano4Secretaría de Salud, Hospital General de México, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoSecretaría de Salud, Hospital General de México, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoBackground: Many studies in children had identified risk factors associated with partly or uncontrolled asthma. In adults, factors related to asthma control were not well defined. Objective: To find the factors related to partly or uncontrolled asthma in adults. Methods: Asthmatic adults who had severity at least in the mild persistent level, were recruited. The asthma control levels were classified as controlled, partly controlled and uncontrolled according to the Global Initiative for Asthma guideline. Risk factors were compared between the patients with controlled and partly controlled/ uncontrolled asthma groups. Results: two hundred (75.5 % females) were included. The mean age was 38.4 ± 11.93 years old. There were 100 patients (50 %) in the controlled and 100 patients (50 %) in partly controlled and uncontrolled asthma group. For asthma severity, 35 patients (88.2 %) were in mild persistent, 14 patients (10 %) in moderate persistent and 97 patients (1.8 %) in severe persistent groups. The absence of stress yielded an OR = 0.41 (95 % CI = 0.23-0.75), p = 0.03. While active smoking, OR = 4.23 (95 % CI = 1.35-13.2), p = 0.007. Patients who have no contact with stuffed animals or rugs have OR = 0.4 (IC 95 % = 0.2-0.79). It was important the result of the patients that if they correctly use their inhalers OR = 0.36 (IC 95 % = 0.13-0.97), p = 0.031. Conclusions: Current and active smoking and atopic dermatitis are risk factors. As a protective factor to the normal levels of eosinophils in blood, correct use of inhalers, FEV1 > 80 %, the absence of stress and the absence of contact with carpets and stuffed animals.http://revistaalergia.mx/ojs/index.php/ram/article/view/557asmaadultosgina |
| spellingShingle | Juan Carlos Fernández de Córdova-Aguirre Andrea Aída Velasco-Medina César Urquiza Karol Andrea Guzmán-Guillén Guillermo Velázquez-Sámano Risk factors for uncontrolled asthma in adults Revista Alergia México asma adultos gina |
| title | Risk factors for uncontrolled asthma in adults |
| title_full | Risk factors for uncontrolled asthma in adults |
| title_fullStr | Risk factors for uncontrolled asthma in adults |
| title_full_unstemmed | Risk factors for uncontrolled asthma in adults |
| title_short | Risk factors for uncontrolled asthma in adults |
| title_sort | risk factors for uncontrolled asthma in adults |
| topic | asma adultos gina |
| url | http://revistaalergia.mx/ojs/index.php/ram/article/view/557 |
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