A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort

Abstract Background The study aimed to estimate the incidence of and period of progression to stage 2 hypertension from normal blood pressure. Methods We selected a total of 21,172 normotensive individuals between 2003 and 2004 from the National Health Insurance Service-Health Screening and followed...

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Main Authors: Eun Sun Yu, Kwan Hong, Byung Chul Chun
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Public Health
Subjects:
Online Access:https://doi.org/10.1186/s12889-020-10115-7
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author Eun Sun Yu
Kwan Hong
Byung Chul Chun
author_facet Eun Sun Yu
Kwan Hong
Byung Chul Chun
author_sort Eun Sun Yu
collection DOAJ
description Abstract Background The study aimed to estimate the incidence of and period of progression to stage 2 hypertension from normal blood pressure. Methods We selected a total of 21,172 normotensive individuals between 2003 and 2004 from the National Health Insurance Service-Health Screening and followed them up until 2015. The criteria for blood pressure were based on the American College of Cardiology/American Heart Association 2017 guideline (normal BP: SBP < 120 and DBP < 80 mmHg, elevated BP: SBP 120–129 and DBP < 80 mmHg, stage 1 hypertension: SBP 130–139 or DBP 80–89 mmHg, stage 2 hypertension: SBP ≥140 or DBP ≥ 90 mmHg). We classified the participants into four courses (Course A: normal BP → elevated BP → stage 1 hypertension→ stage 2 hypertension, Course B: normal BP → elevated BP → stage 2 hypertension, Course C: normal BP → stage 1 hypertension → stage 2 hypertension, Course D: normal BP → stage 2 hypertension) according to their progression from normal blood pressure to stage 2 hypertension. Results During the median 12.23 years of follow-up period, 52.8% (n= 11,168) and 23.6% (n=5004) of the participants had stage 1 and stage 2 hypertension, respectively. In particular, over 60 years old had a 2.8-fold higher incidence of stage 2 hypertension than 40–49 years old. After the follow-up period, 77.5% (n=3879) of participants with stage 2 hypertension were found to be course C (n= 2378) and D (n=1501). After the follow-up period, 77.5% (n=3879) of participants with stage 2 hypertension were found to be course C (n= 2378) and D (n=1501). The mean years of progression from normal blood pressure to stage 2 hypertension were 8.7±2.6 years (course A), 6.1±2.9 years (course B), 7.5±2.8 years (course C) and 3.2±2.0 years, respectively. Conclusions This study found that the incidence of hypertension is associated with the progression at each stage. We suggest that the strategies necessary to prevent progression to stage 2 hypertension need to be set differently for each target course.
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spelling doaj.art-f9e42870a5ae46c38385cec085ea006d2022-12-21T16:52:29ZengBMCBMC Public Health1471-24582021-01-012111810.1186/s12889-020-10115-7A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohortEun Sun Yu0Kwan Hong1Byung Chul Chun2National Health Insurance ServiceKorea University Graduate School of Public HealthKorea University Graduate School of Public HealthAbstract Background The study aimed to estimate the incidence of and period of progression to stage 2 hypertension from normal blood pressure. Methods We selected a total of 21,172 normotensive individuals between 2003 and 2004 from the National Health Insurance Service-Health Screening and followed them up until 2015. The criteria for blood pressure were based on the American College of Cardiology/American Heart Association 2017 guideline (normal BP: SBP < 120 and DBP < 80 mmHg, elevated BP: SBP 120–129 and DBP < 80 mmHg, stage 1 hypertension: SBP 130–139 or DBP 80–89 mmHg, stage 2 hypertension: SBP ≥140 or DBP ≥ 90 mmHg). We classified the participants into four courses (Course A: normal BP → elevated BP → stage 1 hypertension→ stage 2 hypertension, Course B: normal BP → elevated BP → stage 2 hypertension, Course C: normal BP → stage 1 hypertension → stage 2 hypertension, Course D: normal BP → stage 2 hypertension) according to their progression from normal blood pressure to stage 2 hypertension. Results During the median 12.23 years of follow-up period, 52.8% (n= 11,168) and 23.6% (n=5004) of the participants had stage 1 and stage 2 hypertension, respectively. In particular, over 60 years old had a 2.8-fold higher incidence of stage 2 hypertension than 40–49 years old. After the follow-up period, 77.5% (n=3879) of participants with stage 2 hypertension were found to be course C (n= 2378) and D (n=1501). After the follow-up period, 77.5% (n=3879) of participants with stage 2 hypertension were found to be course C (n= 2378) and D (n=1501). The mean years of progression from normal blood pressure to stage 2 hypertension were 8.7±2.6 years (course A), 6.1±2.9 years (course B), 7.5±2.8 years (course C) and 3.2±2.0 years, respectively. Conclusions This study found that the incidence of hypertension is associated with the progression at each stage. We suggest that the strategies necessary to prevent progression to stage 2 hypertension need to be set differently for each target course.https://doi.org/10.1186/s12889-020-10115-7Blood pressureIncidenceStage 2 hypertensionCohort study
spellingShingle Eun Sun Yu
Kwan Hong
Byung Chul Chun
A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort
BMC Public Health
Blood pressure
Incidence
Stage 2 hypertension
Cohort study
title A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort
title_full A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort
title_fullStr A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort
title_full_unstemmed A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort
title_short A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort
title_sort longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension a 12 year korean cohort
topic Blood pressure
Incidence
Stage 2 hypertension
Cohort study
url https://doi.org/10.1186/s12889-020-10115-7
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