Rumen-protected methionine during heat stress alters mTOR, insulin signaling, and 1-carbon metabolism protein abundance in liver, and whole-blood transsulfuration pathway genes in Holstein cows

ABSTRACT: We investigated effects of rumen-protected Met (RPM) during a heat stress (HS) challenge on (1) hepatic abundance of mTOR, insulin, and antioxidant signaling proteins, (2) enzymes in 1-carbon metabolism, and (3) innate immunity. Holstein cows (n = 32; mean ± standard deviation, 184 ± 59 d...

Full description

Bibliographic Details
Main Authors: D.N. Coleman, P. Totakul, N. Onjai-uea, A. Aboragah, Q. Jiang, M. Vailati-Riboni, R.T. Pate, D. Luchini, P. Paengkoum, M. Wanapat, F.C. Cardoso, J.J. Loor
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Journal of Dairy Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030222004076