Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality
Abstract Background Rheumatoid arthritis (RA) is an autoimmune systemic condition that primarily affects all synovial joints, eventually leading to deformity and clinical disability. Much progress has been made in the evaluation of inflammation and disease activity in recent years; however, other fa...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2022-09-01
|
| Series: | Middle East Current Psychiatry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43045-022-00239-4 |
| _version_ | 1811265230239432704 |
|---|---|
| author | Adel Ibrahim Azzam Mohamed Lamlom Ahmed Mohamed Khalifa |
| author_facet | Adel Ibrahim Azzam Mohamed Lamlom Ahmed Mohamed Khalifa |
| author_sort | Adel Ibrahim Azzam |
| collection | DOAJ |
| description | Abstract Background Rheumatoid arthritis (RA) is an autoimmune systemic condition that primarily affects all synovial joints, eventually leading to deformity and clinical disability. Much progress has been made in the evaluation of inflammation and disease activity in recent years; however, other factors that can influence these patients’ quality of life, including depression, stress, fatigue, sleep problems, fibromyalgia, sexual activity, and obesity, are often not evaluated by rheumatologists. Our purpose was to explore depressive symptoms in patients with RA and determine how they connected to other aspects of the disease, including pain severity, disease activity, and sleep quality. Results A cross-sectional study including 1200 patients with RA was performed. Paints with RA were classified into two groups based on the presence or absence of depressive symptoms using the Beck Depression Inventory-II (BDI-II). Group 1 included patients with both RA and depressive symptoms of varying severity; group 2 included patients with RA but without depressive symptoms. The patients underwent clinical evaluation and application of the Pittsburgh Sleep Quality Index (PSQI), Health Assessment Questionnaire for pain (HAQ-pain), and the Multidimensional Assessment of Fatigue scale (MAF). RA disease activity was evaluated using the DAS28 score. Depressive symptoms of varying severity were prevalent in 96% of our patients with RA, of whom 43.3% had minimal depression, while 13.7% had severe depression. The RA group with depression had a longer duration of disease, prolonged morning stiffness, and high disease activity measured by the DAS28 score than patients with only RA. In RA patients with concomitant depression, pain, sleep, and fatigue scores were also worse. Conclusions The presence of depression among patients with RA was associated with worse DAS28, HAQ, PASQI, and fatigue scores. Screening and recognition of such psychosocial disorders may help patients achieve optimal disease control and a good outcome. |
| first_indexed | 2024-04-12T20:19:54Z |
| format | Article |
| id | doaj.art-f9e50cd71efc431c939b360bcc2b93a2 |
| institution | Directory Open Access Journal |
| issn | 2090-5416 |
| language | English |
| last_indexed | 2024-04-12T20:19:54Z |
| publishDate | 2022-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Middle East Current Psychiatry |
| spelling | doaj.art-f9e50cd71efc431c939b360bcc2b93a22022-12-22T03:18:02ZengSpringerOpenMiddle East Current Psychiatry2090-54162022-09-012911710.1186/s43045-022-00239-4Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep qualityAdel Ibrahim Azzam0Mohamed Lamlom1Ahmed Mohamed Khalifa2Department of Rheumatology and Rehabilitation, Faculty of Medicine, Al-Azhar UniversityDepartment of Psychiatry, Faculty of Medicine, Al-Azhar UniversityDepartment of Psychiatry, Faculty of Medicine, Al-Azhar UniversityAbstract Background Rheumatoid arthritis (RA) is an autoimmune systemic condition that primarily affects all synovial joints, eventually leading to deformity and clinical disability. Much progress has been made in the evaluation of inflammation and disease activity in recent years; however, other factors that can influence these patients’ quality of life, including depression, stress, fatigue, sleep problems, fibromyalgia, sexual activity, and obesity, are often not evaluated by rheumatologists. Our purpose was to explore depressive symptoms in patients with RA and determine how they connected to other aspects of the disease, including pain severity, disease activity, and sleep quality. Results A cross-sectional study including 1200 patients with RA was performed. Paints with RA were classified into two groups based on the presence or absence of depressive symptoms using the Beck Depression Inventory-II (BDI-II). Group 1 included patients with both RA and depressive symptoms of varying severity; group 2 included patients with RA but without depressive symptoms. The patients underwent clinical evaluation and application of the Pittsburgh Sleep Quality Index (PSQI), Health Assessment Questionnaire for pain (HAQ-pain), and the Multidimensional Assessment of Fatigue scale (MAF). RA disease activity was evaluated using the DAS28 score. Depressive symptoms of varying severity were prevalent in 96% of our patients with RA, of whom 43.3% had minimal depression, while 13.7% had severe depression. The RA group with depression had a longer duration of disease, prolonged morning stiffness, and high disease activity measured by the DAS28 score than patients with only RA. In RA patients with concomitant depression, pain, sleep, and fatigue scores were also worse. Conclusions The presence of depression among patients with RA was associated with worse DAS28, HAQ, PASQI, and fatigue scores. Screening and recognition of such psychosocial disorders may help patients achieve optimal disease control and a good outcome.https://doi.org/10.1186/s43045-022-00239-4DepressionRADAS28PASQI |
| spellingShingle | Adel Ibrahim Azzam Mohamed Lamlom Ahmed Mohamed Khalifa Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality Middle East Current Psychiatry Depression RA DAS28 PASQI |
| title | Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality |
| title_full | Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality |
| title_fullStr | Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality |
| title_full_unstemmed | Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality |
| title_short | Screening for depressive symptoms in patients with rheumatoid arthritis: relationship with pain severity, disease activity, and sleep quality |
| title_sort | screening for depressive symptoms in patients with rheumatoid arthritis relationship with pain severity disease activity and sleep quality |
| topic | Depression RA DAS28 PASQI |
| url | https://doi.org/10.1186/s43045-022-00239-4 |
| work_keys_str_mv | AT adelibrahimazzam screeningfordepressivesymptomsinpatientswithrheumatoidarthritisrelationshipwithpainseveritydiseaseactivityandsleepquality AT mohamedlamlom screeningfordepressivesymptomsinpatientswithrheumatoidarthritisrelationshipwithpainseveritydiseaseactivityandsleepquality AT ahmedmohamedkhalifa screeningfordepressivesymptomsinpatientswithrheumatoidarthritisrelationshipwithpainseveritydiseaseactivityandsleepquality |