Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation

Gerald V Naccarelli,1 Frank Peacock21Penn State Heart and Vascular institute, Hershey, Pennsylvania, USA; 2Cleveland Clinic, Cleveland, Ohio, USAAbstract: Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and m...

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Main Authors: Gerald V Naccarelli, Frank Peacock
Format: Article
Language:English
Published: Dove Medical Press 2009-09-01
Series:Vascular Health and Risk Management
Online Access:http://www.dovepress.com/angiotensinnbspii-receptor-blockers-in-the-prevention-of-complications-a3537
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author Gerald V Naccarelli
Frank Peacock
author_facet Gerald V Naccarelli
Frank Peacock
author_sort Gerald V Naccarelli
collection DOAJ
description Gerald V Naccarelli,1 Frank Peacock21Penn State Heart and Vascular institute, Hershey, Pennsylvania, USA; 2Cleveland Clinic, Cleveland, Ohio, USAAbstract: Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and mortality, especially due to ischemic stroke. The occurrence of AF leads to atrial electrical and structural remodeling. The renin-angiotensin system appears to play a role in the development of atrial arrhythmias by its involvement in both of these processes. Large-scale hypertension trials and heart failure trials have indicated the potential value of angiotensin II receptor blockers in the treatment of AF.Keywords: angiotensin II receptor blockers, atrial fibrillation, cardiac arrhythmia
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spelling doaj.art-f9e6e3d10ad34001a3ce3209b18193a32022-12-22T01:15:52ZengDove Medical PressVascular Health and Risk Management1176-63441178-20482009-09-012009default783791Angiotensin II receptor blockers in the prevention of complications from atrial fibrillationGerald V NaccarelliFrank PeacockGerald V Naccarelli,1 Frank Peacock21Penn State Heart and Vascular institute, Hershey, Pennsylvania, USA; 2Cleveland Clinic, Cleveland, Ohio, USAAbstract: Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and mortality, especially due to ischemic stroke. The occurrence of AF leads to atrial electrical and structural remodeling. The renin-angiotensin system appears to play a role in the development of atrial arrhythmias by its involvement in both of these processes. Large-scale hypertension trials and heart failure trials have indicated the potential value of angiotensin II receptor blockers in the treatment of AF.Keywords: angiotensin II receptor blockers, atrial fibrillation, cardiac arrhythmiahttp://www.dovepress.com/angiotensinnbspii-receptor-blockers-in-the-prevention-of-complications-a3537
spellingShingle Gerald V Naccarelli
Frank Peacock
Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation
Vascular Health and Risk Management
title Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation
title_full Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation
title_fullStr Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation
title_full_unstemmed Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation
title_short Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation
title_sort angiotensin amp nbsp ii receptor blockers in the prevention of complications from atrial fibrillation
url http://www.dovepress.com/angiotensinnbspii-receptor-blockers-in-the-prevention-of-complications-a3537
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AT frankpeacock angiotensinampnbspiireceptorblockersinthepreventionofcomplicationsfromatrialfibrillation