Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic Programme
Introduction The WHO would increase diagnosis and treatment of viral hepatitis in the world by 2030, based on the high efficacy of direct-acting-antivirals against HCV, extended vaccination programs in HBC, and epidemiological data. Diagnostic of HCV/HBV infection has been simplified by point-of-ca...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2022-06-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933822012214/type/journal_article |
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| author | M. Cavero T. Planas J. Goikolea S. Lens C. Bartrés L. Colomer C. García M. Valentí V. Ruiz Y. Rivas A. Benabarre R. Catalan G. Masana J. Colom X. Forns R. Martin-Santos Z. Mariño |
| author_facet | M. Cavero T. Planas J. Goikolea S. Lens C. Bartrés L. Colomer C. García M. Valentí V. Ruiz Y. Rivas A. Benabarre R. Catalan G. Masana J. Colom X. Forns R. Martin-Santos Z. Mariño |
| author_sort | M. Cavero |
| collection | DOAJ |
| description |
Introduction
The WHO would increase diagnosis and treatment of viral hepatitis in the world by 2030, based on the high efficacy of direct-acting-antivirals against HCV, extended vaccination programs in HBC, and epidemiological data. Diagnostic of HCV/HBV infection has been simplified by point-of-care (POC) devices (cheap/easy-to-use/interprete/qick-results), detecting anti-HCV-antibodies or HBV-antigen in capillary blood at the patients´site. The current seroprevalence of viral hepatitis B/C in general population in Spain is 0.5%/1% and would be higher (3-17%) in people with severe-mental-disorder due to risk factors and traditionally less access to health care.
Objectives
To design a screening protocol for HCV eradication and HBV-detection, and risk factors among severe-mental-disorder patients in a CommunityMentalHealthCenter. To guarantee equal access to viral hepatitis screening and therapy among this population.
Methods
Outpatients visited along one-year who accepts participate. Using POC-device for qualitative detection of anti-HCV-antibodies (Quickview-of-Lumiquick-Diagnostics®)/HBsAG (Abbott-Rapid-Diagnostics®). Socio-demographic data; mental disorder(ICD-10); HCV/HBV risk-factors; Neurotoxicity-scale (mood/cognition/sleep/gastrointestinal/sickness/motor); SF-12; Patient-satisfaction. Subjects with positive HCV/HBV POC-test will have a on-site venopuncture to assess hemograme/liver tests, and HCV-RNA (Cobas-TaqMan-RocheDiagnostics)/HBsAg-ELISA (Atellica-Siemens). In positive HCV-RNA (active infection) the psychiatric-team will inform the hepatology-team for non-invasive liver fibrosis assessment and DAA prescription. The patient will receive 8-12-weeks on-site treatment, and assessed (Neurotoxicity/SF-12).HCV cure will be confirmed by HCV-RNA in blood. Chronic-cases will be managed at Hepatology-Unit.
Results
We will present the results of the implementation of the programme and their ability to detect viral-hepatitis-positive cases among patients with severe-mental-disorders and to treat them effectively.
Conclusions
Our results may support the generalisation of the programme in among CMHC’s.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:53:07Z |
| format | Article |
| id | doaj.art-f9e73a9495f6403cb08ad4261ef5314f |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:53:07Z |
| publishDate | 2022-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-f9e73a9495f6403cb08ad4261ef5314f2023-11-17T05:06:20ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S480S48110.1192/j.eurpsy.2022.1221Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic ProgrammeM. Cavero0T. Planas1J. Goikolea2S. Lens3C. Bartrés4L. Colomer5C. García6M. Valentí7V. Ruiz8Y. Rivas9A. Benabarre10R. Catalan11G. Masana12J. Colom13X. Forns14R. Martin-Santos15Z. Mariño16Hospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , Liver Unit, Barcelona, SpainHospital Clínic, , Liver Unit, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainAgéncia de Salut Pública de Catalunya, Programa Pcavihv, Barcelona, SpainHospital Clínic, , Liver Unit, Barcelona, SpainHospital Clínic, , department Of Psychiatry And Psychology, Barcelona, SpainHospital Clínic, , Liver Unit, Barcelona, Spain Introduction The WHO would increase diagnosis and treatment of viral hepatitis in the world by 2030, based on the high efficacy of direct-acting-antivirals against HCV, extended vaccination programs in HBC, and epidemiological data. Diagnostic of HCV/HBV infection has been simplified by point-of-care (POC) devices (cheap/easy-to-use/interprete/qick-results), detecting anti-HCV-antibodies or HBV-antigen in capillary blood at the patients´site. The current seroprevalence of viral hepatitis B/C in general population in Spain is 0.5%/1% and would be higher (3-17%) in people with severe-mental-disorder due to risk factors and traditionally less access to health care. Objectives To design a screening protocol for HCV eradication and HBV-detection, and risk factors among severe-mental-disorder patients in a CommunityMentalHealthCenter. To guarantee equal access to viral hepatitis screening and therapy among this population. Methods Outpatients visited along one-year who accepts participate. Using POC-device for qualitative detection of anti-HCV-antibodies (Quickview-of-Lumiquick-Diagnostics®)/HBsAG (Abbott-Rapid-Diagnostics®). Socio-demographic data; mental disorder(ICD-10); HCV/HBV risk-factors; Neurotoxicity-scale (mood/cognition/sleep/gastrointestinal/sickness/motor); SF-12; Patient-satisfaction. Subjects with positive HCV/HBV POC-test will have a on-site venopuncture to assess hemograme/liver tests, and HCV-RNA (Cobas-TaqMan-RocheDiagnostics)/HBsAg-ELISA (Atellica-Siemens). In positive HCV-RNA (active infection) the psychiatric-team will inform the hepatology-team for non-invasive liver fibrosis assessment and DAA prescription. The patient will receive 8-12-weeks on-site treatment, and assessed (Neurotoxicity/SF-12).HCV cure will be confirmed by HCV-RNA in blood. Chronic-cases will be managed at Hepatology-Unit. Results We will present the results of the implementation of the programme and their ability to detect viral-hepatitis-positive cases among patients with severe-mental-disorders and to treat them effectively. Conclusions Our results may support the generalisation of the programme in among CMHC’s. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822012214/type/journal_articleviral hepatitisHCVSevere Mental DisordersHBC |
| spellingShingle | M. Cavero T. Planas J. Goikolea S. Lens C. Bartrés L. Colomer C. García M. Valentí V. Ruiz Y. Rivas A. Benabarre R. Catalan G. Masana J. Colom X. Forns R. Martin-Santos Z. Mariño Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic Programme European Psychiatry viral hepatitis HCV Severe Mental Disorders HBC |
| title | Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic Programme |
| title_full | Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic Programme |
| title_fullStr | Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic Programme |
| title_full_unstemmed | Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic Programme |
| title_short | Screnning of viral hepatitis in mental disorder patients: Psiqui-Clinic Programme |
| title_sort | screnning of viral hepatitis in mental disorder patients psiqui clinic programme |
| topic | viral hepatitis HCV Severe Mental Disorders HBC |
| url | https://www.cambridge.org/core/product/identifier/S0924933822012214/type/journal_article |
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