P.58 Genetic Background Dictates Aortic Fibrosis in Hypertensive Mice
Background: Many genetic mutations affect aortic structure and function in mice, but little is known about the influence of background strain. We compared the biomechanical, structural, and gene expression responses of C57BL/6J and 129SvEv aortas to angiotensin II (AngII)-induced hypertension. Meth...
Main Authors: | Bart Spronck, Marcos Latorre, Sameet Mehta, Alexander W. Caulk, Abhay B. Ramachandra, Sae-Il Murtada, Alexia Rojas, Chang-Sun He, Bo Jiang, Mo Wang, Matthew R. Bersi, George Tellides, Jay D. Humphrey |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | Artery Research |
Subjects: | |
Online Access: | https://www.atlantis-press.com/article/125950088/view |
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