Adenoviral expression of a transforming growth factor-β1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats

Adenoviral expression of a transforming growth factor-β1 antisense mRNA is effective in preventing liver fibrosis in bile-duct ligated rats

<p>Abstract</p> <p>Background</p> <p>Transforming growth factor-β (TGF-β) is a key mediator in establishing liver fibrosis. Therefore, TGF-β as a causative agent may serve as a primary target for antifibrotic gene therapy approaches. We have previously shown that the ad...

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Bibliographic Details
Main Authors: Buettner Reinhard, Theuerkauf Ingo, Janoschek Nora, Treptau Jens, Sauer-Lehnen Sibille, Arias Monica, Gressner Axel M, Weiskirchen Ralf
Format: Article
Language:English
Published: BMC 2003-10-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/3/29

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