Subcutaneous Fungal Cyst Masquerading as Benign Lesions – A Series of Eight Cases
Background: Subcutaneous fungal infections are caused by penetration of the causative fungi into the subcutaneous layer and are usually localised. We present a series of eight cases with subcutaneous fungal cystic lesions masquerading as benign lesions. Materials and Methods: A retrospective st...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2015-10-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6637/14157_CE[Ra1]_F(AK)_PF1(EKAK)_PFA(NC_AK)_PF2(PAG).pdf |
| Summary: | Background: Subcutaneous fungal infections are caused by
penetration of the causative fungi into the subcutaneous layer
and are usually localised. We present a series of eight cases
with subcutaneous fungal cystic lesions masquerading as
benign lesions.
Materials and Methods: A retrospective study was conducted
on subcutaneous fungal infections seen between January 2007
to July 2014 in the Department of Pathology. Eight patients with
biopsy proven subcutaneous fungal infection were included.
We collected and analysed their demographic, clinical and
histopathological details.
Results: Among eight patients, six were male and two were
female. The mean age was 47 years (Range: 21-70). All the eight
patients presented with non-tender cystic swelling. The size of
the swellings varied from a minimum of 3x3 cm to maximum of
10x4 cm. Out of eight, hand was involved in three, forearm in
one, elbow in two, leg in one and foot in one. On H&E staining,
all the cases showed fibro collagenous cyst wall, lined by
histiocytes, granulomatous reaction, foreign body type of giant
cells with acute and chronic inflammatory infiltrate containing
fungal elements. Six were identified as hyalohyphomycosis
and two were identified as phaeohyphomycotic cysts based on
pigmentation of hyphae.
Conclusion: Fungal infection should be suspected in all
subcutaneous cystic lesions. Excised tissue should always be
sent for culture and histopathology. |
|---|---|
| ISSN: | 2249-782X 0973-709X |