The clinical utility of Nanopore 16S rRNA gene sequencing for direct bacterial identification in normally sterile body fluids

The clinical utility of Nanopore 16S rRNA gene sequencing for direct bacterial identification in normally sterile body fluids

The prolonged incubation period of traditional culture methods leads to a delay in diagnosing invasive infections. Nanopore 16S rRNA gene sequencing (Nanopore 16S) offers a potential rapid diagnostic approach for directly identifying bacteria in infected body fluids. To evaluate the clinical utility...

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Bibliographic Details
Main Authors: Hiu-Yin Lao, Lily Lok-Yee Wong, Yan Hui, Timothy Ting-Leung Ng, Chloe Toi-Mei Chan, Hazel Wing-Hei Lo, Miranda Chong-Yee Yau, Eddie Chi-Man Leung, River Chun-Wai Wong, Alex Yat-Man Ho, Kam-Tong Yip, Jimmy Yiu-Wing Lam, Viola Chi-Ying Chow, Kristine Shik Luk, Tak-Lun Que, Franklin Wang Ngai Chow, Gilman Kit-Hang Siu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
Nanopore sequencing
16S rRNA gene sequencing
direct bacterial identification
body fluids
rapid diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1324494/full

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