Natural History of Glaucoma Progression in the DBA/2J Model: Early Contribution of Müller Cell Gliosis

Natural History of Glaucoma Progression in the DBA/2J Model: Early Contribution of Müller Cell Gliosis

Glaucoma is a chronic optic neuropathy characterized by progressive degeneration of retinal ganglion cells (RGCs). Elevated intraocular pressure (IOP) and the resulting mechanical stress are classically considered the main causes of RGC death. However, RGC degeneration and ensuing vision loss often...

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Bibliographic Details
Main Authors: Rosario Amato, Maurizio Cammalleri, Alberto Melecchi, Paola Bagnoli, Vittorio Porciatti
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
inherited model
intraocular pressure
vision loss
glial cell reactivity
retinal vasculature
blood–retinal barrier
Online Access:https://www.mdpi.com/2073-4409/12/9/1272

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