Multicenter, Observational Cohort Study Evaluating Third-Generation Cephalosporin Therapy for Bloodstream Infections Secondary to <i>Enterobacter</i>, <i>Serratia</i>, and <i>Citrobacter</i> Species

Multicenter, Observational Cohort Study Evaluating Third-Generation Cephalosporin Therapy for Bloodstream Infections Secondary to <i>Enterobacter</i>, <i>Serratia</i>, and <i>Citrobacter</i> Species

<b>Objectives:</b> There is debate on whether the use of third-generation cephalosporins (3GC) increases the risk of clinical failure in bloodstream infections (BSIs) caused by chromosomally-mediated AmpC-producing Enterobacterales (CAE). This study evaluates the impact of definitive 3GC...

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Bibliographic Details
Main Authors: Caroline Derrick, P. Brandon Bookstaver, Zhiqiang K. Lu, Christopher M. Bland, S. Travis King, Kayla R. Stover, Kathey Rumley, Shawn H. MacVane, Jenna Swindler, Scott Kincaid, Trisha Branan, David Cluck, Benjamin Britt, Kelly E. Pillinger, Bruce M. Jones, Virginia Fleming, V. Paul DiMondi, Sandy Estrada, Brad Crane, Brian Odle, Majdi N. Al-Hasan, Julie Ann Justo
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Antibiotics
Subjects:
bacteremia
cephalosporins
sepsis
beta-lactamases
AmpC
carbapenems
Online Access:https://www.mdpi.com/2079-6382/9/5/254

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