Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset.

Cumulative genetic profiles can help identify individuals at high-risk for developing RA. We examined the impact of 39 validated genetic risk alleles on the risk of RA phenotypes characterized by serologic and erosive status.We evaluated single nucleotide polymorphisms at 31 validated RA risk loci a...

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Bibliographic Details
Main Authors: Lori B Chibnik, Brendan T Keenan, Jing Cui, Katherine P Liao, Karen H Costenbader, Robert M Plenge, Elizabeth W Karlson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3171415?pdf=render