p21-Activated Kinase 1 Is Permissive for the Skeletal Muscle Hypertrophy Induced by Myostatin Inhibition

p21-Activated Kinase 1 Is Permissive for the Skeletal Muscle Hypertrophy Induced by Myostatin Inhibition

Skeletal muscle, the most abundant tissue in the body, plays vital roles in locomotion and metabolism. Understanding the cellular processes that govern regulation of muscle mass and function represents an essential step in the development of therapeutic strategies for muscular disorders. Myostatin,...

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Bibliographic Details
Main Authors:	Caroline Barbé, Audrey Loumaye, Pascale Lause, Olli Ritvos, Jean-Paul Thissen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-06-01
Series:	Frontiers in Physiology
Subjects:	myostatin follistatin sActRIIB PAK1 skeletal muscle hypertrophy
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2021.677746/full

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