The impact of circadian rhythms on the immune response to influenza vaccination in middle-aged and older adults (IMPROVE): a randomised controlled trial

The impact of circadian rhythms on the immune response to influenza vaccination in middle-aged and older adults (IMPROVE): a randomised controlled trial

Abstract Background Vaccination is important in influenza prevention but the immune response wanes with age. The circadian nature of the immune system suggests that adjusting the time of vaccination may provide an opportunity to improve immunogenicity. Our previous cluster trial in Birmingham sugges...

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Bibliographic Details
Main Authors: Yihao Liu, Hui Zhang, Gang Yuan, Mi Yao, Bin Li, Jianying Chen, Yuling Fan, Ruohui Mo, Fenghua Lai, Xinwen Chen, Mengyuan Li, Binfeng Chen, Janet M. Lord, Sui Peng, KarKeung Cheng, Haipeng Xiao
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Immunity & Ageing
Subjects:
Circadian
Immunity
Influenza vaccination
Older adults
Ageing
Online Access:https://doi.org/10.1186/s12979-022-00304-w

Internet

https://doi.org/10.1186/s12979-022-00304-w

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