Setup and Characterization of a High-Throughput Luminescence-Based Serum Bactericidal Assay (L-SBA) to Determine Functionality of Human Sera against <i>Shigella flexneri</i>

Setup and Characterization of a High-Throughput Luminescence-Based Serum Bactericidal Assay (L-SBA) to Determine Functionality of Human Sera against <i>Shigella flexneri</i>

Shigellosis represents a major public health problem worldwide. The morbidity of the disease, especially in children in developing countries, together with the increase of antimicrobial resistance make a vaccine against <i>Shigella</i> an urgent medical need. Several vaccines under devel...

Full description

Bibliographic Details
Main Authors: Francesca Mancini, Francesca Micoli, Omar Rossi
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:BioTech
Subjects:
serum bactericidal assay (SBA)
<i>Shigella flexneri</i>
generalized modules for membrane antigens (GMMA)
functional assay
human
luminescence
Online Access:https://www.mdpi.com/2673-6284/11/3/29

Similar Items

Similar Items