Urgent need for novel antibiotics in Republic of Korea to combat multidrug-resistant bacteria

Multidrug resistance in bacteria is an important issue and is increasing in frequency worldwide because of the limitations of therapeutic agents. From 2010 to 2019, 14 new systemic antibiotics received regulatory approval in the United States. However, few new antibiotics have been introduced in Rep...

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Bibliographic Details
Main Authors: Hyo-Jin Lee, Dong-Gun Lee
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2022-03-01
Series:The Korean Journal of Internal Medicine
Subjects:
Online Access:http://www.kjim.org/upload/pdf/kjim-2021-527.pdf
Description
Summary:Multidrug resistance in bacteria is an important issue and is increasing in frequency worldwide because of the limitations of therapeutic agents. From 2010 to 2019, 14 new systemic antibiotics received regulatory approval in the United States. However, few new antibiotics have been introduced in Republic of Korea to combat multidrug-resistant pathogens. Here, we introduce six novel antibiotics for Gram-positive bacteria and five for Gram-negative bacteria approved by the United States Food and Drug Administration and the European Medicines Agency from 2009 to October 2021, and recommend that they be approved for use in Republic of Korea at the earliest possible date.
ISSN:1226-3303
2005-6648