Angle-stable interlocking nailing in a canine critical-sized femoral defect model for bone regeneration studies: In pursuit of the principle of the 3R’s

Angle-stable interlocking nailing in a canine critical-sized femoral defect model for bone regeneration studies: In pursuit of the principle of the 3R’s

Introduction: Critical-sized long bone defects represent a major therapeutic challenge and current treatment strategies are not without complication. Tissue engineering holds much promise for these debilitating injuries; however, these strategies often fail to successfully translate from rodent stud...

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Bibliographic Details
Main Authors: W. B. Saunders, L. M. Dejardin, E. V. Soltys-Niemann, C. N. Kaulfus, B. M. Eichelberger, L. K. Dobson, B. R. Weeks, S. C. Kerwin, C. A. Gregory
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
canine
large animal model
critical-sized defect
non-union
bone regeneration
interlocking nail
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.921486/full

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