Recent Development in Pulmonary Valve Replacement after Tetralogy of Fallot Repair: The Emergence of Hybrid Approaches

In the current era approximately 90% of infants born with tetralogy of Fallot (ToF) are expected to live beyond 40 years of age making it the fastest growing population amongst patients with congenital heart disease. One of the most common late consequences after repair of ToF, is pulmonary valve re...

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Main Authors: Tariq eSuleiman, Damien eKenny, Clifford J Kavinsky, Clare eSkerritt, Michelle N Ilbawi, Massimo eCaputo
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Surgery
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fsurg.2015.00022/full
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author Tariq eSuleiman
Damien eKenny
Clifford J Kavinsky
Clare eSkerritt
Michelle N Ilbawi
Massimo eCaputo
Massimo eCaputo
author_facet Tariq eSuleiman
Damien eKenny
Clifford J Kavinsky
Clare eSkerritt
Michelle N Ilbawi
Massimo eCaputo
Massimo eCaputo
author_sort Tariq eSuleiman
collection DOAJ
description In the current era approximately 90% of infants born with tetralogy of Fallot (ToF) are expected to live beyond 40 years of age making it the fastest growing population amongst patients with congenital heart disease. One of the most common late consequences after repair of ToF, is pulmonary valve regurgitation (PVR). Significant PVR results in progressive dilatation and dysfunction of the right ventricle, decrease in exercise tolerance, arrhythmias, heart failure, and increased risk of sudden death. The conventional approach of dealing with this problem is to perform pulmonary valve replacement using cardiopulmonary bypass (CPB) and cardioplegic arrest. However, this approach is associated not only with long operative times but also side effects related to the use of CPB. Development of percutaneous approaches to valve disease is one of the most exciting areas of research and clinical innovation in cardiovascular research. The main development has been that of transcatheter pulmonary valve replacement for the rehabilitation of conduits between the right ventricle and pulmonary artery in patients after surgery for ToF. However, with the percutaneous technique, a limited size of prosthesis can be inserted. Moreover, the technique does not offer the opportunity of treating additional defects that are frequently associated with severe PR, such as pulmonary artery dilatation, and it cannot be used in the significantly dilated native right ventricular outlet tract (RVOT). The advent of the hybrid surgical options for treating cardiac disease has integrated the techniques of interventional cardiology with the techniques of cardiac surgery to provide a form of therapy that combines the respective strengths of both fields.In this review, we present and compare recent advances in procedures to replace the pulmonary valve in patients with ToF presenting with severe PVR and dilated RVOT.
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spelling doaj.art-fa072d1b870b455883d1478a955bddc62022-12-22T02:42:49ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2015-06-01210.3389/fsurg.2015.00022141314Recent Development in Pulmonary Valve Replacement after Tetralogy of Fallot Repair: The Emergence of Hybrid ApproachesTariq eSuleiman0Damien eKenny1Clifford J Kavinsky2Clare eSkerritt3Michelle N Ilbawi4Massimo eCaputo5Massimo eCaputo6Rush University Medical CenterRush University Medical CenterRush University Medical CenterRush University Medical CenterRush University Medical CenterUniversity of BristolRush University Medical CenterIn the current era approximately 90% of infants born with tetralogy of Fallot (ToF) are expected to live beyond 40 years of age making it the fastest growing population amongst patients with congenital heart disease. One of the most common late consequences after repair of ToF, is pulmonary valve regurgitation (PVR). Significant PVR results in progressive dilatation and dysfunction of the right ventricle, decrease in exercise tolerance, arrhythmias, heart failure, and increased risk of sudden death. The conventional approach of dealing with this problem is to perform pulmonary valve replacement using cardiopulmonary bypass (CPB) and cardioplegic arrest. However, this approach is associated not only with long operative times but also side effects related to the use of CPB. Development of percutaneous approaches to valve disease is one of the most exciting areas of research and clinical innovation in cardiovascular research. The main development has been that of transcatheter pulmonary valve replacement for the rehabilitation of conduits between the right ventricle and pulmonary artery in patients after surgery for ToF. However, with the percutaneous technique, a limited size of prosthesis can be inserted. Moreover, the technique does not offer the opportunity of treating additional defects that are frequently associated with severe PR, such as pulmonary artery dilatation, and it cannot be used in the significantly dilated native right ventricular outlet tract (RVOT). The advent of the hybrid surgical options for treating cardiac disease has integrated the techniques of interventional cardiology with the techniques of cardiac surgery to provide a form of therapy that combines the respective strengths of both fields.In this review, we present and compare recent advances in procedures to replace the pulmonary valve in patients with ToF presenting with severe PVR and dilated RVOT.http://journal.frontiersin.org/Journal/10.3389/fsurg.2015.00022/fullPulmonary Valve InsufficiencyTetralogy of Fallotcardiac surgerycongenital heart disease (CHD)Hybrid intervention
spellingShingle Tariq eSuleiman
Damien eKenny
Clifford J Kavinsky
Clare eSkerritt
Michelle N Ilbawi
Massimo eCaputo
Massimo eCaputo
Recent Development in Pulmonary Valve Replacement after Tetralogy of Fallot Repair: The Emergence of Hybrid Approaches
Frontiers in Surgery
Pulmonary Valve Insufficiency
Tetralogy of Fallot
cardiac surgery
congenital heart disease (CHD)
Hybrid intervention
title Recent Development in Pulmonary Valve Replacement after Tetralogy of Fallot Repair: The Emergence of Hybrid Approaches
title_full Recent Development in Pulmonary Valve Replacement after Tetralogy of Fallot Repair: The Emergence of Hybrid Approaches
title_fullStr Recent Development in Pulmonary Valve Replacement after Tetralogy of Fallot Repair: The Emergence of Hybrid Approaches
title_full_unstemmed Recent Development in Pulmonary Valve Replacement after Tetralogy of Fallot Repair: The Emergence of Hybrid Approaches
title_short Recent Development in Pulmonary Valve Replacement after Tetralogy of Fallot Repair: The Emergence of Hybrid Approaches
title_sort recent development in pulmonary valve replacement after tetralogy of fallot repair the emergence of hybrid approaches
topic Pulmonary Valve Insufficiency
Tetralogy of Fallot
cardiac surgery
congenital heart disease (CHD)
Hybrid intervention
url http://journal.frontiersin.org/Journal/10.3389/fsurg.2015.00022/full
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