Self-organization in amoeboid motility
Amoeboid motility has come to refer to a spectrum of cell migration modes enabling a cell to move in the absence of strong, specific adhesion. To do so, cells have evolved a range of motile surface movements whose physical principles are now coming into view. In response to external cues, many cells...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Cell and Developmental Biology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2022.1000071/full |
| _version_ | 1811241371147698176 |
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| author | Andrew Callan-Jones |
| author_facet | Andrew Callan-Jones |
| author_sort | Andrew Callan-Jones |
| collection | DOAJ |
| description | Amoeboid motility has come to refer to a spectrum of cell migration modes enabling a cell to move in the absence of strong, specific adhesion. To do so, cells have evolved a range of motile surface movements whose physical principles are now coming into view. In response to external cues, many cells—and some single-celled-organisms—have the capacity to turn off their default migration mode. and switch to an amoeboid mode. This implies a restructuring of the migration machinery at the cell scale and suggests a close link between cell polarization and migration mediated by self-organizing mechanisms. Here, I review recent theoretical models with the aim of providing an integrative, physical picture of amoeboid migration. |
| first_indexed | 2024-04-12T13:35:11Z |
| format | Article |
| id | doaj.art-fa08d17e5ce040afb8f5577cbb70f821 |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-04-12T13:35:11Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-fa08d17e5ce040afb8f5577cbb70f8212022-12-22T03:31:02ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2022-10-011010.3389/fcell.2022.10000711000071Self-organization in amoeboid motilityAndrew Callan-JonesAmoeboid motility has come to refer to a spectrum of cell migration modes enabling a cell to move in the absence of strong, specific adhesion. To do so, cells have evolved a range of motile surface movements whose physical principles are now coming into view. In response to external cues, many cells—and some single-celled-organisms—have the capacity to turn off their default migration mode. and switch to an amoeboid mode. This implies a restructuring of the migration machinery at the cell scale and suggests a close link between cell polarization and migration mediated by self-organizing mechanisms. Here, I review recent theoretical models with the aim of providing an integrative, physical picture of amoeboid migration.https://www.frontiersin.org/articles/10.3389/fcell.2022.1000071/fullactomyosin cortexcortical flowsurface mechanicsactive gel theorymechanochemical feedback |
| spellingShingle | Andrew Callan-Jones Self-organization in amoeboid motility Frontiers in Cell and Developmental Biology actomyosin cortex cortical flow surface mechanics active gel theory mechanochemical feedback |
| title | Self-organization in amoeboid motility |
| title_full | Self-organization in amoeboid motility |
| title_fullStr | Self-organization in amoeboid motility |
| title_full_unstemmed | Self-organization in amoeboid motility |
| title_short | Self-organization in amoeboid motility |
| title_sort | self organization in amoeboid motility |
| topic | actomyosin cortex cortical flow surface mechanics active gel theory mechanochemical feedback |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2022.1000071/full |
| work_keys_str_mv | AT andrewcallanjones selforganizationinamoeboidmotility |