Patient-derived multicellular tumor spheroids towards optimized treatment for patients with hepatocellular carcinoma
Abstract Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide and has poor prognosis. Specially, patients with HCC usually have poor tolerance of systemic chemotherapy, because HCCs develop from chronically damaged tissue that contains considerable inflammat...
Main Authors: | Yeonhwa Song, Jin-Sun Kim, Se-Hyuk Kim, Yoon Kyung Park, Eunsil Yu, Ki-Hun Kim, Eul-Ju Seo, Heung-Bum Oh, Han Chu Lee, Kang Mo Kim, Haeng Ran Seo |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
|
Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13046-018-0752-0 |
Similar Items
-
Anti-Cancer Effects of YAP Inhibitor (CA3) in Combination with Sorafenib against Hepatocellular Carcinoma (HCC) in Patient-Derived Multicellular Tumor Spheroid Models (MCTS)
by: Sojung Han, et al.
Published: (2022-05-01) -
Natural and Synthetic Biomaterials for Engineering Multicellular Tumor Spheroids
by: Advika Kamatar, et al.
Published: (2020-10-01) -
Applications and Advances of Multicellular Tumor Spheroids: Challenges in Their Development and Analysis
by: Achilleas G. Mitrakas, et al.
Published: (2023-04-01) -
GSK-3β regulates the endothelial-to-mesenchymal transition via reciprocal crosstalk between NSCLC cells and HUVECs in multicellular tumor spheroid models
by: Se-Hyuk Kim, et al.
Published: (2019-02-01) -
Recent Advances in Multicellular Tumor Spheroid Generation for Drug Screening
by: Kwang-Ho Lee, et al.
Published: (2021-11-01)