Stable DNA Aptamer–Metal–Organic Framework as Horseradish Peroxidase Mimic for Ultra-Sensitive Detection of Carcinoembryonic Antigen in Serum

Stable DNA Aptamer–Metal–Organic Framework as Horseradish Peroxidase Mimic for Ultra-Sensitive Detection of Carcinoembryonic Antigen in Serum

Carcinoembryonic antigen (CEA) is an important broad-spectrum tumor marker. For CEA detection, a novel type of metal–organic framework (MOF) was prepared by grafting CEA aptamer-incorporated DNA tetrahedral (TDN) nanostructures into PCN-222 (Fe)-based MOF (referred as CEA<sub>apt</sub>-T...

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Bibliographic Details
Main Authors: Lingjun Sha, Mingcong Zhu, Fuqing Lin, Xiaomeng Yu, Langjian Dong, Licheng Wu, Rong Ding, Shuai Wu, Jingjing Xu
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Gels
Subjects:
colloid nanorods
DNA tetrahedron nanostructure
catalytic oxidation
carcinoembryonic antigen
colorimetric detection
Online Access:https://www.mdpi.com/2310-2861/7/4/181

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