Characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosis
Objective. Evaluation of skin sensitivity and analysis of morphological changes in paravertebral muscles and back skin in kyphoscoliotic deformity projection in patients with type 1 neurofibromatosis (NF-1).Materials and methods. Ten NF-1 patients who underwent surgery to treat kyphoscoliosis were e...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2017-05-01
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| Series: | Нервно-мышечные болезни |
| Subjects: | |
| Online Access: | https://nmb.abvpress.ru/jour/article/view/195 |
| _version_ | 1826558127273672704 |
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| author | E. N. Shchurova E. N. Gorbach G. N. Filimonova S. O. Ryabykh E. N. Ochirova |
| author_facet | E. N. Shchurova E. N. Gorbach G. N. Filimonova S. O. Ryabykh E. N. Ochirova |
| author_sort | E. N. Shchurova |
| collection | DOAJ |
| description | Objective. Evaluation of skin sensitivity and analysis of morphological changes in paravertebral muscles and back skin in kyphoscoliotic deformity projection in patients with type 1 neurofibromatosis (NF-1).Materials and methods. Ten NF-1 patients who underwent surgery to treat kyphoscoliosis were examined. Using an electrical esthesiometer thermal pain sensitivity before the surgery was studied in dermatomes corresponding to the apex of the deformity. Skin and muscle biopsy samples were collected intraoperatively in the projection of the apex of the deformity curve and were subsequently analyzed by light and scanning electron microscopy.Results. Patients with kyphoscoliosis with underlying NF-1 were characterized by abnormal thermal pain sensitivity, pathological structural changes in skin and muscles accompanied by disrupted innervation and blood supply.Discussion. The observed changes may be responsible for lowered postoperative reparative potential of tissues and they must be considered in prevention and prognosis of treatment and rehabilitation efficacy. |
| first_indexed | 2024-03-12T03:13:43Z |
| format | Article |
| id | doaj.art-fa118345f7c244538a3a978d05fde085 |
| institution | Directory Open Access Journal |
| issn | 2222-8721 2413-0443 |
| language | Russian |
| last_indexed | 2025-03-14T08:39:33Z |
| publishDate | 2017-05-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Нервно-мышечные болезни |
| spelling | doaj.art-fa118345f7c244538a3a978d05fde0852025-03-02T12:54:42ZrusABV-pressНервно-мышечные болезни2222-87212413-04432017-05-0171303610.17650/2222-8721-2017-7-1-30-36168Characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosisE. N. Shchurova0E. N. Gorbach1G. N. Filimonova2S. O. Ryabykh3E. N. Ochirova4G. A. Ilizarov Russian Scientific Center оf Restorative Traumatology and Orthopedics, Ministry of Health of RussiaG. A. Ilizarov Russian Scientific Center оf Restorative Traumatology and Orthopedics, Ministry of Health of RussiaG. A. Ilizarov Russian Scientific Center оf Restorative Traumatology and Orthopedics, Ministry of Health of RussiaG. A. Ilizarov Russian Scientific Center оf Restorative Traumatology and Orthopedics, Ministry of Health of RussiaG. A. Ilizarov Russian Scientific Center оf Restorative Traumatology and Orthopedics, Ministry of Health of RussiaObjective. Evaluation of skin sensitivity and analysis of morphological changes in paravertebral muscles and back skin in kyphoscoliotic deformity projection in patients with type 1 neurofibromatosis (NF-1).Materials and methods. Ten NF-1 patients who underwent surgery to treat kyphoscoliosis were examined. Using an electrical esthesiometer thermal pain sensitivity before the surgery was studied in dermatomes corresponding to the apex of the deformity. Skin and muscle biopsy samples were collected intraoperatively in the projection of the apex of the deformity curve and were subsequently analyzed by light and scanning electron microscopy.Results. Patients with kyphoscoliosis with underlying NF-1 were characterized by abnormal thermal pain sensitivity, pathological structural changes in skin and muscles accompanied by disrupted innervation and blood supply.Discussion. The observed changes may be responsible for lowered postoperative reparative potential of tissues and they must be considered in prevention and prognosis of treatment and rehabilitation efficacy.https://nmb.abvpress.ru/jour/article/view/195type 1 neurofibromatosiskyphoscoliosisapex of the deformitythermal and pain sensitivityskinparavertebral muscles |
| spellingShingle | E. N. Shchurova E. N. Gorbach G. N. Filimonova S. O. Ryabykh E. N. Ochirova Characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosis Нервно-мышечные болезни type 1 neurofibromatosis kyphoscoliosis apex of the deformity thermal and pain sensitivity skin paravertebral muscles |
| title | Characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosis |
| title_full | Characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosis |
| title_fullStr | Characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosis |
| title_full_unstemmed | Characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosis |
| title_short | Characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosis |
| title_sort | characteristics of soft tissues at the apex of the deformity in patients with kyphoscoliosis with underlying type 1 neurofibromatosis |
| topic | type 1 neurofibromatosis kyphoscoliosis apex of the deformity thermal and pain sensitivity skin paravertebral muscles |
| url | https://nmb.abvpress.ru/jour/article/view/195 |
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