Loss of Nuclear/DNA Integrity in Mouse Epididymal Spermatozoa after Short-Term Exposure to Low Doses of Dibutyl Phthalate or Bisphenol AF and Its Mitigation by Oral Antioxidant Supplementation

Loss of Nuclear/DNA Integrity in Mouse Epididymal Spermatozoa after Short-Term Exposure to Low Doses of Dibutyl Phthalate or Bisphenol AF and Its Mitigation by Oral Antioxidant Supplementation

Routine exposure to chemicals omnipresent in the environment, particularly the so-called endocrine-disrupting chemicals (EDCs), has been associated with decreased sperm quality and increased anomalies in testis. The decline in semen quality and testicular abnormalities have been attributed to the di...

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Bibliographic Details
Main Authors: Elisa Hug, Pauline Villeneuve, Stephanie Bravard, Areski Chorfa, Christelle Damon-Soubeyrand, Stephen G. Somkuti, Aron Moazamian, R. John Aitken, Parviz Gharagozloo, Joël R. Drevet, Fabrice Saez
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Antioxidants
Subjects:
endocrine disruptors
environmental pollutants
oxidative stress
DNA damage
spermatozoa
male fertility
Online Access:https://www.mdpi.com/2076-3921/12/5/1046

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