Kikuchi-Fujimoto Disease: a Case Report

Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is an idiopathic, self-limiting disorder and predominantly affects young women. We report a 35-year-old female who presented with soft to firm cervical lymphadenopathy and neck pain. She had multiple enlarged cervical nodes. Examinati...

Full description

Bibliographic Details
Main Authors: Mozaffar Aznab, Naser Kamalian, Jaffar Navabi, Kaveh Kavianimoghadam
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-11-01
Series:Acta Medica Iranica
Subjects:
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/5019
_version_ 1818644166159106048
author Mozaffar Aznab
Naser Kamalian
Jaffar Navabi
Kaveh Kavianimoghadam
author_facet Mozaffar Aznab
Naser Kamalian
Jaffar Navabi
Kaveh Kavianimoghadam
author_sort Mozaffar Aznab
collection DOAJ
description Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is an idiopathic, self-limiting disorder and predominantly affects young women. We report a 35-year-old female who presented with soft to firm cervical lymphadenopathy and neck pain. She had multiple enlarged cervical nodes. Examination of other systems was normal. Lymph node biopsy was performed, and the histological features, and immunohistochemistry confirmed the diagnosis. The Patient was treated with non-steroidal anti-inflammatory drugs and low-dose prednisolone. A significant decrease in the size of lymph node and relief of neck pain occurred. During four years of follow-up, the patient developed no malignant disease or systemic and autoimmune diseases such as systemic lupus erythematosus. Kikuchi-Fujimoto disease is rare, clinicians should be aware of this condition as early diagnosis of the disease will lessen concerns of the patient's family.
first_indexed 2024-12-17T00:10:31Z
format Article
id doaj.art-fa14752023654f948119c0341128a3ed
institution Directory Open Access Journal
issn 0044-6025
1735-9694
language English
last_indexed 2024-12-17T00:10:31Z
publishDate 2015-11-01
publisher Tehran University of Medical Sciences
record_format Article
series Acta Medica Iranica
spelling doaj.art-fa14752023654f948119c0341128a3ed2022-12-21T22:10:51ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942015-11-0153114903Kikuchi-Fujimoto Disease: a Case ReportMozaffar Aznab0Naser Kamalian1Jaffar Navabi2Kaveh Kavianimoghadam3Department of Internal Medicine, Taleghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran.Department of Internal Medicine, Taleghani Hospital, Kermanshah, Iran.Department of Paramedical, School of Medicine, Kermanshah of University Medical Sciences, Kermanshah, Iran.Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is an idiopathic, self-limiting disorder and predominantly affects young women. We report a 35-year-old female who presented with soft to firm cervical lymphadenopathy and neck pain. She had multiple enlarged cervical nodes. Examination of other systems was normal. Lymph node biopsy was performed, and the histological features, and immunohistochemistry confirmed the diagnosis. The Patient was treated with non-steroidal anti-inflammatory drugs and low-dose prednisolone. A significant decrease in the size of lymph node and relief of neck pain occurred. During four years of follow-up, the patient developed no malignant disease or systemic and autoimmune diseases such as systemic lupus erythematosus. Kikuchi-Fujimoto disease is rare, clinicians should be aware of this condition as early diagnosis of the disease will lessen concerns of the patient's family.https://acta.tums.ac.ir/index.php/acta/article/view/5019Kikuchi-Fujimoto diseaseHistiocytic necrotizing lymphadenitis
spellingShingle Mozaffar Aznab
Naser Kamalian
Jaffar Navabi
Kaveh Kavianimoghadam
Kikuchi-Fujimoto Disease: a Case Report
Acta Medica Iranica
Kikuchi-Fujimoto disease
Histiocytic necrotizing lymphadenitis
title Kikuchi-Fujimoto Disease: a Case Report
title_full Kikuchi-Fujimoto Disease: a Case Report
title_fullStr Kikuchi-Fujimoto Disease: a Case Report
title_full_unstemmed Kikuchi-Fujimoto Disease: a Case Report
title_short Kikuchi-Fujimoto Disease: a Case Report
title_sort kikuchi fujimoto disease a case report
topic Kikuchi-Fujimoto disease
Histiocytic necrotizing lymphadenitis
url https://acta.tums.ac.ir/index.php/acta/article/view/5019
work_keys_str_mv AT mozaffaraznab kikuchifujimotodiseaseacasereport
AT naserkamalian kikuchifujimotodiseaseacasereport
AT jaffarnavabi kikuchifujimotodiseaseacasereport
AT kavehkavianimoghadam kikuchifujimotodiseaseacasereport