An integrated proteomic and glycoproteomic approach uncovers differences in glycosylation occupancy from benign and malignant epithelial ovarian tumors

An integrated proteomic and glycoproteomic approach uncovers differences in glycosylation occupancy from benign and malignant epithelial ovarian tumors

Abstract Background Epithelial ovarian carcinomas encompass a heterogeneous group of diseases with a poor 5-year survival rate. Serous carcinoma is the most common type. Most FDA-approved serum tumor markers are glycoproteins. These glycoproteins on cell surface or shed into the bloodstream could se...

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Bibliographic Details
Main Authors: Qing Kay Li, Punit Shah, Yuan Tian, Yingwei Hu, Richard B. S. Roden, Hui Zhang, Daniel W. Chan
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Clinical Proteomics
Subjects:
Ovarian high-grade serous carcinoma
Proteomics
Glycoproteomics
Online Access:http://link.springer.com/article/10.1186/s12014-017-9152-2

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