Current approaches to diagnosis, treatment, and monitoring in patients with cryopyrin-associated periodic syndromes (CAPS)
Cryopyrin-associated periodic syndromes (CAPS) are the most prominent representatives of monogenic autoinflammatory diseases (AIDs). They are characterized by a concurrence of fever, rash, and other symptoms that are accompanied by disabling or life-threatening complications. Based on the current gu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2016-06-01
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| Series: | Современная ревматология |
| Subjects: | |
| Online Access: | https://mrj.ima-press.net/mrj/article/view/677 |
| _version_ | 1826556937497477120 |
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| author | S. O. Salugina E. S. Fedorov N. N. Kuzmina |
| author_facet | S. O. Salugina E. S. Fedorov N. N. Kuzmina |
| author_sort | S. O. Salugina |
| collection | DOAJ |
| description | Cryopyrin-associated periodic syndromes (CAPS) are the most prominent representatives of monogenic autoinflammatory diseases (AIDs). They are characterized by a concurrence of fever, rash, and other symptoms that are accompanied by disabling or life-threatening complications. Based on the current guidelines for the management of patients with AIDs and on their own experience, the authors have elaborated a diagnostic algorithm for CAPS, which can optimize their differential diagnosis with systemic juvenile arthritis and other AIDs and the early use of effective therapy and management tactics. Interleukin-1 inhibitors are target agents, by which one can monitor activity and prevent complications. The given algorithm will be able to improve the timely diagnosis of CAPS and to optimize treat-to-target treatment and management in patients. |
| first_indexed | 2024-04-10T02:08:04Z |
| format | Article |
| id | doaj.art-fa17e28c5f854db484ba831d27687916 |
| institution | Directory Open Access Journal |
| issn | 1996-7012 2310-158X |
| language | Russian |
| last_indexed | 2025-03-14T08:20:38Z |
| publishDate | 2016-06-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj.art-fa17e28c5f854db484ba831d276879162025-03-02T13:10:58ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2016-06-0110241110.14412/1996-7012-2016-2-4-111968Current approaches to diagnosis, treatment, and monitoring in patients with cryopyrin-associated periodic syndromes (CAPS)S. O. Salugina0E. S. Fedorov1N. N. Kuzmina2V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115552V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115552V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia 34A, Kashirskoe Shosse, Moscow 115552Cryopyrin-associated periodic syndromes (CAPS) are the most prominent representatives of monogenic autoinflammatory diseases (AIDs). They are characterized by a concurrence of fever, rash, and other symptoms that are accompanied by disabling or life-threatening complications. Based on the current guidelines for the management of patients with AIDs and on their own experience, the authors have elaborated a diagnostic algorithm for CAPS, which can optimize their differential diagnosis with systemic juvenile arthritis and other AIDs and the early use of effective therapy and management tactics. Interleukin-1 inhibitors are target agents, by which one can monitor activity and prevent complications. The given algorithm will be able to improve the timely diagnosis of CAPS and to optimize treat-to-target treatment and management in patients.https://mrj.ima-press.net/mrj/article/view/677cryopyrin-associated periodic syndromes (caps)guidelinestreatmentmonitoringinterleukin-1 inhibitorscanakinumab |
| spellingShingle | S. O. Salugina E. S. Fedorov N. N. Kuzmina Current approaches to diagnosis, treatment, and monitoring in patients with cryopyrin-associated periodic syndromes (CAPS) Современная ревматология cryopyrin-associated periodic syndromes (caps) guidelines treatment monitoring interleukin-1 inhibitors canakinumab |
| title | Current approaches to diagnosis, treatment, and monitoring in patients with cryopyrin-associated periodic syndromes (CAPS) |
| title_full | Current approaches to diagnosis, treatment, and monitoring in patients with cryopyrin-associated periodic syndromes (CAPS) |
| title_fullStr | Current approaches to diagnosis, treatment, and monitoring in patients with cryopyrin-associated periodic syndromes (CAPS) |
| title_full_unstemmed | Current approaches to diagnosis, treatment, and monitoring in patients with cryopyrin-associated periodic syndromes (CAPS) |
| title_short | Current approaches to diagnosis, treatment, and monitoring in patients with cryopyrin-associated periodic syndromes (CAPS) |
| title_sort | current approaches to diagnosis treatment and monitoring in patients with cryopyrin associated periodic syndromes caps |
| topic | cryopyrin-associated periodic syndromes (caps) guidelines treatment monitoring interleukin-1 inhibitors canakinumab |
| url | https://mrj.ima-press.net/mrj/article/view/677 |
| work_keys_str_mv | AT sosalugina currentapproachestodiagnosistreatmentandmonitoringinpatientswithcryopyrinassociatedperiodicsyndromescaps AT esfedorov currentapproachestodiagnosistreatmentandmonitoringinpatientswithcryopyrinassociatedperiodicsyndromescaps AT nnkuzmina currentapproachestodiagnosistreatmentandmonitoringinpatientswithcryopyrinassociatedperiodicsyndromescaps |