Antibiotic resistance of colonized in children with staphylococcal scalded skin syndrome
ObjectivesSystemic antibiotic therapy with semisynthetic penicillinase-resistant penicillin or vancomycin and clindamycin are recommended for the treatment of staphylococcal scalded skin syndrome (SSSS). This study assessed the rate of antibiotic resistance of Staphylococcus aureus isolated from the...
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| Format: | Article |
| Language: | English |
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Kosin University College of Medicine
2018-06-01
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| Series: | Kosin Medical Journal |
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| Online Access: | http://www.kosinmedj.org/upload/pdf/ksmc033-01-02.pdf |
| _version_ | 1811192641179615232 |
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| author | Seom Gim Kong |
| author_facet | Seom Gim Kong |
| author_sort | Seom Gim Kong |
| collection | DOAJ |
| description | ObjectivesSystemic antibiotic therapy with semisynthetic penicillinase-resistant penicillin or vancomycin and clindamycin are recommended for the treatment of staphylococcal scalded skin syndrome (SSSS). This study assessed the rate of antibiotic resistance of Staphylococcus aureus isolated from the anterior nares or skin of children diagnosed with SSSS. MethodsA retrospective review of the medical records of 25 patients with SSSS between July 2010 and October 2014 was conducted. The clinical characteristics of patients were collected and the antibiotic susceptibility of S. aureus were analyzed using automated systems. ResultsThe median age of the patients was 22 months (range: 2-95). Ninety-two percent of patients were less than 5 years of age. Nasal swab samples of all patients and skin swab samples of 17 patients were cultured to isolate S. aureus. Twenty-one (84%) of 25 patients were colonized with methicillin-resistant S. aureus (MRSA). The results of swab samples of the other four patients were no growth or isolation of bacteria other than S. aureus. Among 20 strains isolated from the anterior nares, 1 strain (5%) was methicillin-susceptible S. aureus. All 15 strains isolated from the skin were MRSA. All 21 strains isolated from anterior nares or skin were found to be resistant to clindamycin upon evaluation using automated systems. ConclusionsThe rates of methicillin and clindamycin resistance in S. aureus colonized in children with SSSS were very high. Further studies evaluating proper antibiotic regimens and the effectiveness of systemic antibiotic therapy are needed. |
| first_indexed | 2024-04-11T23:55:46Z |
| format | Article |
| id | doaj.art-fa25dd5980bc421a948cf05a62a0d32f |
| institution | Directory Open Access Journal |
| issn | 2005-9531 2586-7024 |
| language | English |
| last_indexed | 2024-04-11T23:55:46Z |
| publishDate | 2018-06-01 |
| publisher | Kosin University College of Medicine |
| record_format | Article |
| series | Kosin Medical Journal |
| spelling | doaj.art-fa25dd5980bc421a948cf05a62a0d32f2022-12-22T03:56:22ZengKosin University College of MedicineKosin Medical Journal2005-95312586-70242018-06-01331121910.7180/kmj.2018.33.1.12204Antibiotic resistance of colonized in children with staphylococcal scalded skin syndromeSeom Gim KongObjectivesSystemic antibiotic therapy with semisynthetic penicillinase-resistant penicillin or vancomycin and clindamycin are recommended for the treatment of staphylococcal scalded skin syndrome (SSSS). This study assessed the rate of antibiotic resistance of Staphylococcus aureus isolated from the anterior nares or skin of children diagnosed with SSSS. MethodsA retrospective review of the medical records of 25 patients with SSSS between July 2010 and October 2014 was conducted. The clinical characteristics of patients were collected and the antibiotic susceptibility of S. aureus were analyzed using automated systems. ResultsThe median age of the patients was 22 months (range: 2-95). Ninety-two percent of patients were less than 5 years of age. Nasal swab samples of all patients and skin swab samples of 17 patients were cultured to isolate S. aureus. Twenty-one (84%) of 25 patients were colonized with methicillin-resistant S. aureus (MRSA). The results of swab samples of the other four patients were no growth or isolation of bacteria other than S. aureus. Among 20 strains isolated from the anterior nares, 1 strain (5%) was methicillin-susceptible S. aureus. All 15 strains isolated from the skin were MRSA. All 21 strains isolated from anterior nares or skin were found to be resistant to clindamycin upon evaluation using automated systems. ConclusionsThe rates of methicillin and clindamycin resistance in S. aureus colonized in children with SSSS were very high. Further studies evaluating proper antibiotic regimens and the effectiveness of systemic antibiotic therapy are needed.http://www.kosinmedj.org/upload/pdf/ksmc033-01-02.pdfbacterialchildcolonizationdrug resistancestaphylococcal scalded skin syndrome |
| spellingShingle | Seom Gim Kong Antibiotic resistance of colonized in children with staphylococcal scalded skin syndrome Kosin Medical Journal bacterial child colonization drug resistance staphylococcal scalded skin syndrome |
| title | Antibiotic resistance of colonized in children with staphylococcal scalded skin syndrome |
| title_full | Antibiotic resistance of colonized in children with staphylococcal scalded skin syndrome |
| title_fullStr | Antibiotic resistance of colonized in children with staphylococcal scalded skin syndrome |
| title_full_unstemmed | Antibiotic resistance of colonized in children with staphylococcal scalded skin syndrome |
| title_short | Antibiotic resistance of colonized in children with staphylococcal scalded skin syndrome |
| title_sort | antibiotic resistance of colonized in children with staphylococcal scalded skin syndrome |
| topic | bacterial child colonization drug resistance staphylococcal scalded skin syndrome |
| url | http://www.kosinmedj.org/upload/pdf/ksmc033-01-02.pdf |
| work_keys_str_mv | AT seomgimkong antibioticresistanceofcolonizedinchildrenwithstaphylococcalscaldedskinsyndrome |