Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary Planning
Introduction. Herpes simplex (HSV) and varicella zoster (VZV) viruses are harmful infectious agents in pregnancy due to their ability to impact maternal-fetal dyads through various modalities including vertical transmission, neonatal infection, and maternal morbidity. As a result, accurate diagnosis...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2024-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2024/1937661 |
| _version_ | 1797201019737735168 |
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| author | Brenna Cook Caroline Shadowen Lorna Clark Alena Hoover Stephanie Lee Whitney Bender |
| author_facet | Brenna Cook Caroline Shadowen Lorna Clark Alena Hoover Stephanie Lee Whitney Bender |
| author_sort | Brenna Cook |
| collection | DOAJ |
| description | Introduction. Herpes simplex (HSV) and varicella zoster (VZV) viruses are harmful infectious agents in pregnancy due to their ability to impact maternal-fetal dyads through various modalities including vertical transmission, neonatal infection, and maternal morbidity. As a result, accurate diagnosis and prompt treatment of these infections in pregnancy is critical. Case. A 19-year-old primigravida presented to our tertiary care center at 30 weeks’ gestation with vulvar swelling, burning, and pain. Workup included direct PCR testing of a particularly erythematous area of the vulva which returned positive for VZV. The patient was treated with a 10-day course of acyclovir with resolution of her symptoms. She later had a full-term spontaneous vaginal delivery outside of the infectious window with no significant morbidity for either her or her neonate. Conclusion. Although a rare presentation, the presence of a genital lesion or labial swelling during pregnancy warrants workup for VZV, particularly among patients known to be varicella nonimmune. If genital VZV is diagnosed during pregnancy, the development of contingency plans through interdisciplinary collaboration should be pursued to ensure a safe delivery and postpartum course for both the maternal-fetal dyad as well as other patients on the unit and the provider care team. |
| first_indexed | 2024-04-24T07:40:53Z |
| format | Article |
| id | doaj.art-fa27d2d8bbdb4178aeac2f2f45d30607 |
| institution | Directory Open Access Journal |
| issn | 2090-6633 |
| language | English |
| last_indexed | 2024-04-24T07:40:53Z |
| publishDate | 2024-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj.art-fa27d2d8bbdb4178aeac2f2f45d306072024-04-20T00:00:01ZengHindawi LimitedCase Reports in Infectious Diseases2090-66332024-01-01202410.1155/2024/1937661Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary PlanningBrenna Cook0Caroline Shadowen1Lorna Clark2Alena Hoover3Stephanie Lee4Whitney Bender5School of MedicineDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologySchool of MedicineSchool of MedicineIntroduction. Herpes simplex (HSV) and varicella zoster (VZV) viruses are harmful infectious agents in pregnancy due to their ability to impact maternal-fetal dyads through various modalities including vertical transmission, neonatal infection, and maternal morbidity. As a result, accurate diagnosis and prompt treatment of these infections in pregnancy is critical. Case. A 19-year-old primigravida presented to our tertiary care center at 30 weeks’ gestation with vulvar swelling, burning, and pain. Workup included direct PCR testing of a particularly erythematous area of the vulva which returned positive for VZV. The patient was treated with a 10-day course of acyclovir with resolution of her symptoms. She later had a full-term spontaneous vaginal delivery outside of the infectious window with no significant morbidity for either her or her neonate. Conclusion. Although a rare presentation, the presence of a genital lesion or labial swelling during pregnancy warrants workup for VZV, particularly among patients known to be varicella nonimmune. If genital VZV is diagnosed during pregnancy, the development of contingency plans through interdisciplinary collaboration should be pursued to ensure a safe delivery and postpartum course for both the maternal-fetal dyad as well as other patients on the unit and the provider care team.http://dx.doi.org/10.1155/2024/1937661 |
| spellingShingle | Brenna Cook Caroline Shadowen Lorna Clark Alena Hoover Stephanie Lee Whitney Bender Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary Planning Case Reports in Infectious Diseases |
| title | Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary Planning |
| title_full | Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary Planning |
| title_fullStr | Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary Planning |
| title_full_unstemmed | Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary Planning |
| title_short | Genital VZV in a Third Trimester Pregnancy and the Critical Role of Interdisciplinary Planning |
| title_sort | genital vzv in a third trimester pregnancy and the critical role of interdisciplinary planning |
| url | http://dx.doi.org/10.1155/2024/1937661 |
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