Anti-cancer potential of polysaccharide extracted from hawthorn (Crataegus.) on human colon cancer cell line HCT116 via cell cycle arrest and apoptosis

Anti-cancer potential of polysaccharide extracted from hawthorn (Crataegus.) on human colon cancer cell line HCT116 via cell cycle arrest and apoptosis

This study demonstrated that a homogeneous polysaccharide (HPS) extracted from Hawthorn exerted anti-cancer effects on colon cancer cells. Human colon cancer cell line HCT116 were treated with 125–1000 µg/mL HPS for 12 h and subsequent analysis was performed on proliferation and signaling pathways....

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Bibliographic Details
Main Authors: Lei Ma, Guanying Bianca Xu, Xinyu Tang, Cheng Zhang, Wen Zhao, Jie Wang, Hong Chen
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Functional Foods
Subjects:
Homogeneous polysaccharide
Colon cancer
Cell cycle
Proliferation
Phospho-AKT
MAPK
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619306012

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