Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases
Background: Initially, novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) was considered primarily a respiratory pathogen. However, with time it has behaved as a virus with the potential to cause multi-system involvement, including neurological manifestations which varies from acute to...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Interdisciplinary Neurosurgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221475192200113X |
| _version_ | 1811336114864128000 |
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| author | Mahmoud M. Taha Mazen M. Taha Hassan A. Al Menshawy Ahmad M. Elsharkawy |
| author_facet | Mahmoud M. Taha Mazen M. Taha Hassan A. Al Menshawy Ahmad M. Elsharkawy |
| author_sort | Mahmoud M. Taha |
| collection | DOAJ |
| description | Background: Initially, novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) was considered primarily a respiratory pathogen. However, with time it has behaved as a virus with the potential to cause multi-system involvement, including neurological manifestations which varies from acute to subacute onset of headache, seizures, a decrease of consciousness, and paralysis. Case description: Two cases of cerebral sinus venous thrombosis in COVID-19 patients were reported, following respiratory disorders, which was triggered by the SARS-CoV-2 infection. The first patient, presented with a decrease in level of consciousness and hemiparesis, was 23 years old female having no history of previous medical co-morbidities. The latter case, 21 years old woman showed less severe presentations of COVID-19 associated with headache, vomiting and papilledema. These two cases marvellously improved with no neurological deficit with aggressive course of anticoagulation. Conclusion: CVST should be suspected in COVID-19 patients presenting with headache, paralysis, aphasia or seizures. The high mortality rate of CVST in COVID-19 infection warrants a high index of suspicion from physicians, and early treatment with anticoagulation should be initiated. |
| first_indexed | 2024-04-13T17:34:43Z |
| format | Article |
| id | doaj.art-fa2a0993b7084634a468583d15d6be2a |
| institution | Directory Open Access Journal |
| issn | 2214-7519 |
| language | English |
| last_indexed | 2024-04-13T17:34:43Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Interdisciplinary Neurosurgery |
| spelling | doaj.art-fa2a0993b7084634a468583d15d6be2a2022-12-22T02:37:27ZengElsevierInterdisciplinary Neurosurgery2214-75192022-09-0129101599Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 casesMahmoud M. Taha0Mazen M. Taha1Hassan A. Al Menshawy2Ahmad M. Elsharkawy3Department of Neurosurgery, Zagazig University, Zagazig, EgyptFaculty of Medicine, Zagazig University, Zagazig, EgyptDepartment of Neurosurgery, AlMokatam Insurance Hospital, Cairo, EgyptDepartment of Neurosurgery, Zagazig University, Zagazig, Egypt; Corresponding author at: Department of Neurosurgery, Zagazig University, P.O.BOX 44512, Zagazig, Egypt.Background: Initially, novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) was considered primarily a respiratory pathogen. However, with time it has behaved as a virus with the potential to cause multi-system involvement, including neurological manifestations which varies from acute to subacute onset of headache, seizures, a decrease of consciousness, and paralysis. Case description: Two cases of cerebral sinus venous thrombosis in COVID-19 patients were reported, following respiratory disorders, which was triggered by the SARS-CoV-2 infection. The first patient, presented with a decrease in level of consciousness and hemiparesis, was 23 years old female having no history of previous medical co-morbidities. The latter case, 21 years old woman showed less severe presentations of COVID-19 associated with headache, vomiting and papilledema. These two cases marvellously improved with no neurological deficit with aggressive course of anticoagulation. Conclusion: CVST should be suspected in COVID-19 patients presenting with headache, paralysis, aphasia or seizures. The high mortality rate of CVST in COVID-19 infection warrants a high index of suspicion from physicians, and early treatment with anticoagulation should be initiated.http://www.sciencedirect.com/science/article/pii/S221475192200113XCorona virus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Cerebral venous sinus thrombosis (CVST)Venous thrombotic events (VTE)Neurologic manifestations |
| spellingShingle | Mahmoud M. Taha Mazen M. Taha Hassan A. Al Menshawy Ahmad M. Elsharkawy Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases Interdisciplinary Neurosurgery Corona virus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Cerebral venous sinus thrombosis (CVST) Venous thrombotic events (VTE) Neurologic manifestations |
| title | Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases |
| title_full | Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases |
| title_fullStr | Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases |
| title_full_unstemmed | Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases |
| title_short | Cerebral venous sinus thrombosis in COVID 19 patients: Report of 2 cases |
| title_sort | cerebral venous sinus thrombosis in covid 19 patients report of 2 cases |
| topic | Corona virus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Cerebral venous sinus thrombosis (CVST) Venous thrombotic events (VTE) Neurologic manifestations |
| url | http://www.sciencedirect.com/science/article/pii/S221475192200113X |
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