Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones
Herein, we report the synthesis of 5,12-dihydropyrazino[2,3-<i>c</i>:5,6-<i>c</i>′]difuro[2,3-<i>c</i>:4,5-<i>c</i>′]-diquinoline-6,14(<i>5H</i>,12<i>H</i>)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-10-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/24/20/3782 |
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| author | Ashraf A. Aly Alaa A. Hassan Nasr K. Mohamed Lamiaa E. Abd El-Haleem Stefan Bräse Mika Polamo Martin Nieger Alan B. Brown |
| author_facet | Ashraf A. Aly Alaa A. Hassan Nasr K. Mohamed Lamiaa E. Abd El-Haleem Stefan Bräse Mika Polamo Martin Nieger Alan B. Brown |
| author_sort | Ashraf A. Aly |
| collection | DOAJ |
| description | Herein, we report the synthesis of 5,12-dihydropyrazino[2,3-<i>c</i>:5,6-<i>c</i>′]difuro[2,3-<i>c</i>:4,5-<i>c</i>′]-diquinoline-6,14(<i>5H</i>,12<i>H</i>)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-1,4-diphenyl- butane-1,4-diones and 4-(benzo-[<i>d</i>]oxazol-2-yl)-3-hydroxy-1<i>H</i>-[4,5]oxazolo[3,2-<i>a</i>]pyridine-1-one. The new candidates were synthesized and identified by different spectroscopic techniques, and X-ray crystallography. |
| first_indexed | 2024-12-10T07:32:25Z |
| format | Article |
| id | doaj.art-fa2c9dc5debc41b99c7b6ad4fa6642da |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-10T07:32:25Z |
| publishDate | 2019-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-fa2c9dc5debc41b99c7b6ad4fa6642da2022-12-22T01:57:32ZengMDPI AGMolecules1420-30492019-10-012420378210.3390/molecules24203782molecules24203782Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-QuinolonesAshraf A. Aly0Alaa A. Hassan1Nasr K. Mohamed2Lamiaa E. Abd El-Haleem3Stefan Bräse4Mika Polamo5Martin Nieger6Alan B. Brown7Chemistry Department, Faculty of Science, Minia University, El-Minia 61519, EgyptChemistry Department, Faculty of Science, Minia University, El-Minia 61519, EgyptChemistry Department, Faculty of Science, Minia University, El-Minia 61519, EgyptChemistry Department, Faculty of Science, Minia University, El-Minia 61519, EgyptInstitute of Organic Chemistry, Karlsruhe Institute of Technology, 76131 Karlsruhe, GermanyDepartment of Chemistry, University of Helsinki, P.O. Box 55 (A. I. Virtasen aukio I), 00014 Helsinki, FinlandDepartment of Chemistry, University of Helsinki, P.O. Box 55 (A. I. Virtasen aukio I), 00014 Helsinki, FinlandChemistry Program, Florida Institute of Technology, Melbourne, FL 32901, USAHerein, we report the synthesis of 5,12-dihydropyrazino[2,3-<i>c</i>:5,6-<i>c</i>′]difuro[2,3-<i>c</i>:4,5-<i>c</i>′]-diquinoline-6,14(<i>5H</i>,12<i>H</i>)diones, 2-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-1,4-diphenyl- butane-1,4-diones and 4-(benzo-[<i>d</i>]oxazol-2-yl)-3-hydroxy-1<i>H</i>-[4,5]oxazolo[3,2-<i>a</i>]pyridine-1-one. The new candidates were synthesized and identified by different spectroscopic techniques, and X-ray crystallography.https://www.mdpi.com/1420-3049/24/20/37826,7-disubstituted-4-hydroxy-quinoline-2-ones2,3-dichloropyrazineanrorc process bis-pyrazinofuro-quinoline1,4-diphenylbutane-1,4-dionesnmrx-ray |
| spellingShingle | Ashraf A. Aly Alaa A. Hassan Nasr K. Mohamed Lamiaa E. Abd El-Haleem Stefan Bräse Mika Polamo Martin Nieger Alan B. Brown Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones Molecules 6,7-disubstituted-4-hydroxy-quinoline-2-ones 2,3-dichloropyrazine anrorc process bis-pyrazinofuro-quinoline 1,4-diphenylbutane-1,4-diones nmr x-ray |
| title | Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones |
| title_full | Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones |
| title_fullStr | Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones |
| title_full_unstemmed | Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones |
| title_short | Synthesis of New Fused Heterocyclic 2-Quinolones and 3-Alkanonyl-4-Hydroxy-2-Quinolones |
| title_sort | synthesis of new fused heterocyclic 2 quinolones and 3 alkanonyl 4 hydroxy 2 quinolones |
| topic | 6,7-disubstituted-4-hydroxy-quinoline-2-ones 2,3-dichloropyrazine anrorc process bis-pyrazinofuro-quinoline 1,4-diphenylbutane-1,4-diones nmr x-ray |
| url | https://www.mdpi.com/1420-3049/24/20/3782 |
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