Diagnosis and management of intramural ectopic pregnancy

Background: Intramural pregnancy is a rare form of ectopic pregnancy where the embryo is implanted within the myometrium, separate from the endometrial cavity. Preoperative diagnosis of intramural pregnancy is difficult and it can easily be misdiagnosed for other diseases such as intrauterine pregna...

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Main Authors: Qian Hu, Mohammed Sharooq Paramboor, Tao Guo
Format: Article
Language:English
Published: IMR Press 2021-08-01
Series:Clinical and Experimental Obstetrics & Gynecology
Subjects:
Online Access:https://www.imrpress.com/journal/CEOG/48/4/10.31083/j.ceog4804154
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author Qian Hu
Mohammed Sharooq Paramboor
Tao Guo
author_facet Qian Hu
Mohammed Sharooq Paramboor
Tao Guo
author_sort Qian Hu
collection DOAJ
description Background: Intramural pregnancy is a rare form of ectopic pregnancy where the embryo is implanted within the myometrium, separate from the endometrial cavity. Preoperative diagnosis of intramural pregnancy is difficult and it can easily be misdiagnosed for other diseases such as intrauterine pregnancy or gestational trophoblastic disease. Medical therapy and surgery are used to treat intramural pregnancy, with surgery often being performed via laparotomy and also including hysterectomy. Case: We present a case of intramural pregnancy that was misdiagnosed and wrongly managed by a local hospital. It was finally diagnosed correctly and managed in our hospital by combining hysteroscopy and laparoscopy under the guidance of intra-abdominal ultrasound. Our experience again highlights the difficulty in diagnosing intramural pregnancy preoperatively due to the lack of standard diagnostic criteria. This can in turn lead to inappropriate treatments. Earlier surgical intervention would allow faster diagnosis and also simultaneous treatment of the disease. The majority of intramural ectopic pregnancies have high blood flow that can cause severe hemorrhage and are therefore treated by medication or laparotomy and hysterectomy. Conclusion: Our experience reveals that a minimally invasive procedure is also safe and effective in select cases where advanced endoscopic expertise is available.
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spelling doaj.art-fa2d1253d3bb4057b618e73a8c416dc02022-12-22T00:38:58ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-08-0148497497910.31083/j.ceog4804154S0390-6663(21)00172-XDiagnosis and management of intramural ectopic pregnancyQian Hu0Mohammed Sharooq Paramboor1Tao Guo2Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Department of Pediatrics, West China Second University Hospital, Sichuan University, 610041 Chengdu, Sichuan, ChinaWest China Medical School, Sichuan University, 610041 Chengdu, Sichuan, ChinaLaboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Department of Pediatrics, West China Second University Hospital, Sichuan University, 610041 Chengdu, Sichuan, ChinaBackground: Intramural pregnancy is a rare form of ectopic pregnancy where the embryo is implanted within the myometrium, separate from the endometrial cavity. Preoperative diagnosis of intramural pregnancy is difficult and it can easily be misdiagnosed for other diseases such as intrauterine pregnancy or gestational trophoblastic disease. Medical therapy and surgery are used to treat intramural pregnancy, with surgery often being performed via laparotomy and also including hysterectomy. Case: We present a case of intramural pregnancy that was misdiagnosed and wrongly managed by a local hospital. It was finally diagnosed correctly and managed in our hospital by combining hysteroscopy and laparoscopy under the guidance of intra-abdominal ultrasound. Our experience again highlights the difficulty in diagnosing intramural pregnancy preoperatively due to the lack of standard diagnostic criteria. This can in turn lead to inappropriate treatments. Earlier surgical intervention would allow faster diagnosis and also simultaneous treatment of the disease. The majority of intramural ectopic pregnancies have high blood flow that can cause severe hemorrhage and are therefore treated by medication or laparotomy and hysterectomy. Conclusion: Our experience reveals that a minimally invasive procedure is also safe and effective in select cases where advanced endoscopic expertise is available.https://www.imrpress.com/journal/CEOG/48/4/10.31083/j.ceog4804154intramural ectopic pregnancyminimally invasive surgerydiagnosis and management
spellingShingle Qian Hu
Mohammed Sharooq Paramboor
Tao Guo
Diagnosis and management of intramural ectopic pregnancy
Clinical and Experimental Obstetrics & Gynecology
intramural ectopic pregnancy
minimally invasive surgery
diagnosis and management
title Diagnosis and management of intramural ectopic pregnancy
title_full Diagnosis and management of intramural ectopic pregnancy
title_fullStr Diagnosis and management of intramural ectopic pregnancy
title_full_unstemmed Diagnosis and management of intramural ectopic pregnancy
title_short Diagnosis and management of intramural ectopic pregnancy
title_sort diagnosis and management of intramural ectopic pregnancy
topic intramural ectopic pregnancy
minimally invasive surgery
diagnosis and management
url https://www.imrpress.com/journal/CEOG/48/4/10.31083/j.ceog4804154
work_keys_str_mv AT qianhu diagnosisandmanagementofintramuralectopicpregnancy
AT mohammedsharooqparamboor diagnosisandmanagementofintramuralectopicpregnancy
AT taoguo diagnosisandmanagementofintramuralectopicpregnancy