Network meta-analysis for clinicians
Decision making in clinical practice requires consideration of the relative efficacy and safety of medical interventions. A systematic review and meta-analysis, the results of which have the highest level of confidence in evidence-based medicine, only compare the effectiveness of two interventions,...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IP Habib O.N.
2021-11-01
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| Series: | Современная онкология |
| Subjects: | |
| Online Access: | https://modernonco.orscience.ru/1815-1434/article/viewFile/88099/66223 |
| _version_ | 1819180249790808064 |
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| author | Alexey A. Bogdanov Andrey A. Bogdanov |
| author_facet | Alexey A. Bogdanov Andrey A. Bogdanov |
| author_sort | Alexey A. Bogdanov |
| collection | DOAJ |
| description | Decision making in clinical practice requires consideration of the relative efficacy and safety of medical interventions. A systematic review and meta-analysis, the results of which have the highest level of confidence in evidence-based medicine, only compare the effectiveness of two interventions, provided that there is a direct comparison between them in a set of randomized controlled trials. The development of statistical methods has led to the development of the network meta-analysis method, the application of which allows comparison for more than two interventions and even if the interventions were not directly compared in randomized controlled trials, but have a common comparison intervention. As a result, network meta-analysis is increasingly being used as an evidence base for the effectiveness of medical interventions. However, there are important assumptions and conditions underlying the performance of network meta-analysis. In this work, we tried to outline the main aspects of network meta-analysis that are important for clinicians in terms of its implementation and interpretation of its results. |
| first_indexed | 2024-12-22T22:11:21Z |
| format | Article |
| id | doaj.art-fa2deff846204e8e9fb53c4c9515d510 |
| institution | Directory Open Access Journal |
| issn | 1815-1434 1815-1442 |
| language | Russian |
| last_indexed | 2024-12-22T22:11:21Z |
| publishDate | 2021-11-01 |
| publisher | IP Habib O.N. |
| record_format | Article |
| series | Современная онкология |
| spelling | doaj.art-fa2deff846204e8e9fb53c4c9515d5102022-12-21T18:10:53ZrusIP Habib O.N.Современная онкология1815-14341815-14422021-11-0123341842410.26442/18151434.2021.3.20120278773Network meta-analysis for cliniciansAlexey A. Bogdanov0https://orcid.org/0000-0002-7887-4635Andrey A. Bogdanov1Saint Petersburg Clinical Research and Practice Centre for Specialized Types of Medical Care (Oncological)Saint Petersburg Clinical Research and Practice Centre for Specialized Types of Medical Care (Oncological)Decision making in clinical practice requires consideration of the relative efficacy and safety of medical interventions. A systematic review and meta-analysis, the results of which have the highest level of confidence in evidence-based medicine, only compare the effectiveness of two interventions, provided that there is a direct comparison between them in a set of randomized controlled trials. The development of statistical methods has led to the development of the network meta-analysis method, the application of which allows comparison for more than two interventions and even if the interventions were not directly compared in randomized controlled trials, but have a common comparison intervention. As a result, network meta-analysis is increasingly being used as an evidence base for the effectiveness of medical interventions. However, there are important assumptions and conditions underlying the performance of network meta-analysis. In this work, we tried to outline the main aspects of network meta-analysis that are important for clinicians in terms of its implementation and interpretation of its results.https://modernonco.orscience.ru/1815-1434/article/viewFile/88099/66223evidence-based medicinecomparative effectiveness of medical interventionsnetwork meta-analysis |
| spellingShingle | Alexey A. Bogdanov Andrey A. Bogdanov Network meta-analysis for clinicians Современная онкология evidence-based medicine comparative effectiveness of medical interventions network meta-analysis |
| title | Network meta-analysis for clinicians |
| title_full | Network meta-analysis for clinicians |
| title_fullStr | Network meta-analysis for clinicians |
| title_full_unstemmed | Network meta-analysis for clinicians |
| title_short | Network meta-analysis for clinicians |
| title_sort | network meta analysis for clinicians |
| topic | evidence-based medicine comparative effectiveness of medical interventions network meta-analysis |
| url | https://modernonco.orscience.ru/1815-1434/article/viewFile/88099/66223 |
| work_keys_str_mv | AT alexeyabogdanov networkmetaanalysisforclinicians AT andreyabogdanov networkmetaanalysisforclinicians |